Alzheimer disease prevention: Focus on cardiovascular risk, not amyloid?

被引：7

作者：

Geldmacher, David S. ^{[1
]}

机构：

[1] Univ Virginia Hlth Syst, Dept Neurol, Charlottesville, VA 22903 USA

来源：

CLEVELAND CLINIC JOURNAL OF MEDICINE | 2010年 / 77卷 / 10期

关键词：

DIABETES-MELLITUS; DEMENTIA;

D O I：

10.3949/ccjm.77gr.2010

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Autosomal dominant (early-onset) Alzheimer disease and the much more common sporadic Alzheimer disease share a common pathology but not necessarily a common pathophysiology. Common cardiovascular comorbidities are associated with increased risk for Alzheimer disease and offer opportunities for intervention. Class I evidence for prevention is extremely limited. The overall body of evidence suggests the best time to intervene is in midlife, not in old age.

引用

页码：689 / +

页数：6

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