Tumor growth-promoting properties of macrophage migration inhibitory factor (MIF)

被引：134
|
作者：
Mitchell, RA [1 ]
Bucala, R [1 ]
机构：
[1] Picower Inst Med Res, Manhasset, NY 11030 USA
来源：
SEMINARS IN CANCER BIOLOGY | 2000年 / 10卷 / 05期
关键词：
angiogenesis; MAP kinases; macrophage migration inhibitory factor; MIF; proliferation;
D O I：
10.1006/scbi.2000.0328
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
First identified nt al nearly 40 years ago, macrophage migration inhibitory factor (MIF) is a potent pro-inflammatory cytokine and is an essential component of immune and inflammatory responses. Recent studies suggest that MIF may also contribute to multiple aspects of tumor progression and neoplasia. This review will attempt to summarize these findings focusing on MIF's ability to modulate cell proliferation, tumor. angiogenesis and tumor suppressor activity.
引用
收藏
页码：359 / 366
页数：8
相关论文
共 50 条
  • [41] Macrophage migration inhibitory factor (MIF) of golden pompano (Trachinotus ovatus) is involved in the antibacterial immune response
    Zhang, Zhengshi
    Hu, Xiucong
    Diao, Qianying
    Zhang, Panpan
    Wu, Ying
    Cao, Zhenjie
    Zhou, Yongcan
    Liu, Chunsheng
    Sun, Yun
    DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY, 2022, 133
  • [42] Expression and regulation of macrophage migration inhibitory factor (MIF) in feeding American dog ticks, Dermacentor variabilis
    Nalinda B. Wasala
    C. J. Bowen
    Deborah C. Jaworski
    Experimental and Applied Acarology, 2012, 57 : 179 - 187
  • [43] Presence of macrophage migration inhibitory factor (MIF) in ependyma, astrocytes and neurons in the bovine brain
    Nishibori, M
    Nakaya, N
    Tahara, A
    Kawabata, M
    Mori, S
    Saeki, K
    NEUROSCIENCE LETTERS, 1996, 213 (03) : 193 - 196
  • [44] Assessment of Serum Macrophage Migration Inhibitory Factor (MIF) as an Early Diagnostic Marker of Leptospirosis
    Sumaiya, Krishnamoorthi
    Akino Mercy, Charles Solomon
    Muralitharan, Gangatharan
    Hajinur Hirad, Abdurahman
    Alarfaj, Abdullah A.
    Natarajaseenivasan, Kalimuthusamy
    FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY, 2022, 11
  • [45] Targeting macrophage migration inhibitory factor (MIF): a promising therapy for inflammatory ocular diseases
    Vazquez, Alicia
    Gonzalez, Marisol I.
    Reyes, Jose L.
    JOURNAL OF OPHTHALMIC INFLAMMATION AND INFECTION, 2023, 13 (01)
  • [46] Identification of macrophage migration inhibitory factor (MIF) in human skin and its immunohistochemical localization
    Shimizu, T
    Ohkawara, A
    Nishihira, J
    Sakamoto, W
    FEBS LETTERS, 1996, 381 (03) : 199 - 202
  • [47] Macrophage migration inhibitory factor (MIF) gene is associated with adolescents' cortisol reactivity and anxiety
    Lipschutz, Rebecca
    Bick, Johanna
    Nguyen, Victoria
    Lee, Maria
    Leng, Lin
    Grigorenko, Elena
    Bucala, Richard
    Mayes, Linda C.
    Crowley, Michael J.
    PSYCHONEUROENDOCRINOLOGY, 2018, 95 : 170 - 178
  • [48] Enhancement of macrophage migration inhibitory factor (MIF) expression in injured epidermis and cultured fibroblasts
    Abe, R
    Shimizu, T
    Ohkawara, AA
    Nishihira, J
    BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE, 2000, 1500 (01): : 1 - 9
  • [49] Targeting macrophage migration inhibitory factor (MIF): a promising therapy for inflammatory ocular diseases
    Alicia Vázquez
    Marisol I. González
    José L. Reyes
    Journal of Ophthalmic Inflammation and Infection, 13
  • [50] Characterization and expression of macrophage migration inhibitory factor (mif) in Chinese sturgeon (Acipenser sinensis)
    Jiang, Nan
    Ni, Qi
    Fan, Yuding
    Wu, Shuwang
    Zhou, Yong
    Liu, Wenzhi
    Si, Kaige
    Zhang, Haigeng
    Robert, Jacques
    Zeng, Lingbing
    FISH & SHELLFISH IMMUNOLOGY, 2020, 103 : 9 - 16
12345