Improving the biocompatibility of NiTi alloy by chemical treatments:: An in vitro evaluation in 3T3 human fibroblast cell

被引：24

作者：

Cui, Z. D. ^{[1
]}

Chen, M. F. ^{[1
,2
]}

Zhang, L. Y. ^{[3
]}

Hu, R. X. ^{[1
]}

Zhu, S. L. ^{[1
]}

Yang, X. J. ^{[1
]}

机构：

[1] Tianjin Univ, Sch Mat Sci & Engn, Tianjin 300072, Peoples R China

[2] Tianjin Univ Technol, Dept Mat Sci & Engn, Tianjin 300191, Peoples R China

[3] Tianjin Med Univ, Tianjin 300070, Peoples R China

来源：

MATERIALS SCIENCE & ENGINEERING C-BIOMIMETIC AND SUPRAMOLECULAR SYSTEMS | 2008年 / 28卷 / 07期

关键词：

NiTi alloy; calcium phosphates coating; biocompatibility; cell cultures;

D O I：

10.1016/j.msec.2007.05.006

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

The nearly equi-atomic nickel titanium alloy was coated with calcium phosphates by socking the chemically treated alloy in simulated body fluid in order to prepare bioactive NiTi implants. The biocompatibility of the calcium phosphates coated NiTi alloy was investigated by in vitro 3T3 human embryonic fibroblast cell culture tests. The cells attachment and morphologies were studied using phase contrast light microscope and environmental scanning electron microscope. The mechanically polished and the calcium phosphates coated NiTi samples were well tolerated by the cells, whereas, the controlled pure Ni samples exhibited strong toxicity to the cells. Furthermore, the calcium phosphates coated NiTi samples showed good osteoconductivity. (c) 2007 Elsevier B.V. All rights reserved.

引用

页码：1117 / 1122

页数：6

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