Friedel-Crafts Alkylation of Indoles with Nitroalkenes Catalyzed by Zn(II)-Thiourea Complex

被引：20

作者：

Wan Ningning ^{[1
,2
]}

Hui Yonghai ^{[1
,2
]}

Xie Zhengfeng ^{[1
]}

Wang Jide ^{[2
]}

机构：

[1] Xinjiang Univ, Minist Educ, Kay Lab Oil & Gas Fine Chem, Urumqi 830046, Xingjiang, Peoples R China

[2] Xinjiang Univ, Coll Chem & Chem Engn, Urumqi 830046, Xingjiang, Peoples R China

来源：

CHINESE JOURNAL OF CHEMISTRY | 2012年 / 30卷 / 02期

基金：

中国国家自然科学基金;

关键词：

Friedel-Crafts alkylation; indole; nitroalkene; thiourea; catalysis; MICHAEL ADDITION; PRACTICAL SYNTHESIS; FACILE SYNTHESIS; PYRROLE; ACID; BIS(INDOLYL)ALKANES; NITROOLEFINS; DERIVATIVES; THIOUREA; IMINES;

D O I：

10.1002/cjoc.201180480

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Friedel-Crafts alkylation of indoles with nitroalkenes catalyzed by a novel Zn(II)-thiourea complex has been developed. The remarkable advantages of this reaction are mild reaction conditions, simple workup procedure, high yield of products and the use of ethanol as acceptable solvent.

引用

页码：311 / 315

页数：5

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