Synthesis and antimicrobial evaluation of novel pyrazolo[1,5-a]pyrimidine, triazolo[1,5-a]pyrimidine and pyrimido[1,2-a]benzimidazole derivatives

被引：0
|
作者：
Shaaban, Mohamed R. [1 ]
Saleh, Tamer S. [1 ]
Farag, Ahmad M. [1 ]
机构：
[1] Cairo Univ, Fac Sci, Dept Chem, Giza 12613, Egypt
来源：
HETEROCYCLES | 2007年 / 71卷 / 08期
关键词：
2-acetylbenzimidazole; pyrazolo[1,5-a]pyrimidine; triazolo[1,5-a]pyrimidine; pyrimido[1,2-a]benzimidazole; antimicrobiol activity;
D O I：
暂无
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The applicability and synthetic potency of E-1-(1-methylbenzimidazol-2-yl)-3-N,N-dimethylaminoprop-2-enone towards some nitrogen nucleophiles was investigated as a convenient route for the synthesis of some novel aminopyrimidine, pyrazolo[1,5-a]pyrimidine, triazolo[1,5-a]pyrimidine, pyrimido[1,2-a]benzimidazole, and pyrido[2,3-d]pyrimidine derivatives. Some of the newly synthesized compounds were tested in vitro for their antibacterial and antifungal activities, and showed promising results.
引用
收藏
页码：1765 / 1777
页数：13
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