New Furostanol Glycosides from the Roots of Digitalis ciliata TRAUTV.

被引：7

作者：

Kemertelidze, Ether ^{[1
]}

Skhirtladze, Alexander ^{[1
]}

Ganzera, Markus ^{[2
]}

机构：

[1] Iovel Kutateladze Inst Pharmacochem, Tbilisi 0159, Georgia

[2] Univ Innsbruck, Inst Pharm, AT-6020 Innsbruck, Austria

来源：

HELVETICA CHIMICA ACTA | 2015年 / 98卷 / 02期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1002/hlca.201400077

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Three new furostanol glycosides, named ciliatasides A, B, and C (1-3, resp.), have been isolated from the roots of Digitalis ciliata, along with two known furostanol glycosides. The structures of the new compounds were identified as (2 alpha, 3 beta, 5 alpha, 14 beta, 25R)-26-(beta-D-glucopyranosyloxy)-2-hydroxyfurost-20(22)-en-3-yl beta-D-glucopyranosyl-(1 -> 2)-[beta-D-glucopyranosyl-(1 -> 3)]-beta-D-galactopyranoside (1), (2 alpha, 3 beta, 5 alpha, 14 beta, 22R)-26-(beta-D-glucopyranosyloxy)-2-hydroxy-22-methoxyfurost-25(27)-en-3-yl beta-D-galactopyranosyl-(1 -> 2)-[beta-D-xylopyranosyl-(1 -> 3)]-beta-D-glucopyranosyl-(1 -> 4)-beta-D-galactopyranoside (2), and (2 alpha, 3 beta, 5 alpha, 14 beta, 22R, 25R)-26-(beta-D-glucopyranosyloxy)-2,22-dihydroxyfurostan-3-yl beta-D-glucopyranosyl-(1 -> 2)-[beta-D-glucopyranosyl-(1 -> 3)]-beta-D-galactopyranoside (3).

引用

页码：224 / 231

页数：8

共 12 条

[1] Dependence of 1H NMR chemical shifts of geminal protons of glycosyloxy methylene (H2-26) on the orientation of the 27-methyl group of furostane-type steroidal saponins
Agrawal, PK
[J]. MAGNETIC RESONANCE IN CHEMISTRY, 2004, 42 (11) : 990 - 993
[2] Belitz H.-D., 2009, Food Chemistry, V4th, P374
[3] Kemertelidze E. P., 1973, Patent UK, Patent No. 1317839
[4] Kemertelidze E. P., 1977, TBILISI METSNIEREBA, P173
[5] Kemertelidze E. P., 1976, Patent DE, Patent No. [21414101976, 2141410]
[6] DIGITOSIDE, A NOVEL TRITERPENE GLYCOSIDE FROM DIGITALIS-CILIATA
KEMERTELIDZE, EP
GVAZAVA, LN
ALANIA, MD
KIKOLADZE, VS
TSITSISHVILI, VG
[J]. JOURNAL OF NATURAL PRODUCTS, 1992, 55 (02): : 217 - 220
[7] Steroidal glycosides from the bulbs of Bessera elegans and their cytotoxic activities
Matsuo, Yukiko
Akagi, Nana
Hashimoto, Chisato
Tachikawa, Fumito
Mimaki, Yoshihiro
[J]. PHYTOCHEMISTRY, 2013, 96 : 244 - 256
[8] Antiproliferative steroidal glycosides from Digitalis ciliata
Perrone, Angela
Capasso, Anna
Festa, Michela
Kemertelidze, Ether
Pizza, Cosimo
Skhirtladze, Alexandre
Piacente, Sonia
[J]. FITOTERAPIA, 2012, 83 (03) : 554 - 562
[9] Shishkin B. K., 1955, FLORA USSR, V22, P521
[10] Furostanol saponins from Yucca gloriosa L. rhizomes
Skhirtladze, Alexandre
Plaza, Alberto
Montoro, Paola
Benidze, Mariam
Kemertelidze, Ether
Pizza, Cosimo
Piacente, Sonia
[J]. BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2006, 34 (11) : 809 - 814

← 1 2 →