Carboplatin-Based Chemotherapy and Surgery: A Cost Effective Treatment Strategy for Malignant Extracranial Germ Cell Tumours in the Developing World

被引：4

作者：

Hendricks, Marc ^{[1
]}

Davidson, Alan ^{[1
]}

Pillay, Komala ^{[2
]}

Desai, Farieda ^{[1
]}

Millar, Alastair ^{[3
]}

机构：

[1] Univ Cape Town, Red Cross War Mem Childrens Hosp, Paediat Haematol Oncol Serv, ZA-7925 Cape Town, South Africa

[2] Univ Cape Town, Red Cross War Mem Childrens Hosp, Natl Hlth Lab Serv, Serv Anat Pathol, ZA-7925 Cape Town, South Africa

[3] Univ Cape Town, Red Cross War Mem Childrens Hosp, Dept Paediat Surg, ZA-7925 Cape Town, South Africa

来源：

PEDIATRIC BLOOD & CANCER | 2011年 / 57卷 / 01期

关键词：

carboplatin-based chemotherapy; malignant extracranial germ cell tumours; COMBINATION CHEMOTHERAPY; ETOPOSIDE; BLEOMYCIN; CHILDREN; CANCER; CISPLATIN; REGIMENS;

D O I：

10.1002/pbc.23055

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Nineteen children with malignant extracranial germ cell tumours (MEGCT), were treated at our institution with a combination of carboplatin-based chemotherapy and surgery from 1992 to 2008. Seventeen are long term survivors. Chemotherapy was administered on an outpatient basis and required no monitoring of GFR or auditory function. There were no deaths from toxicity or infection. Blood product use was low. Carboplatin-based therapy achieved excellent results in our patient population and constitutes more than a US $1,800 saving per patient compared to regimens containing cisplatin. This has application in resource limited settings. Pediatr Blood Cancer 2011;57:172-174. (C) 2011 Wiley-Liss, Inc.

引用

页码：172 / 174

页数：3