Protein structure prediction servers at university college london

被引:598
作者
Bryson, K [1 ]
McGuffin, LJ [1 ]
Marsden, RL [1 ]
Ward, JJ [1 ]
Sodhi, JS [1 ]
Jones, DT [1 ]
机构
[1] UCL, Dept Comp Sci, London WC1E 6BT, England
基金
英国惠康基金;
关键词
D O I
10.1093/nar/gki410
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A number of state-of-the-art protein structure prediction servers have been developed by researchers working in the Bioinformatics Unit at University College London. The popular PSIPRED server allows users to perform secondary structure prediction, transmembrane topology prediction and protein fold recognition. More recent servers include DISOPRED for the prediction of protein dynamic disorder and DomPred for domain boundary prediction. These servers are available from our software home page at http://bioinf.cs.ucl.ac.uk/software.html.
引用
收藏
页码:W36 / W38
页数:3
相关论文
共 14 条
[1]   Gapped BLAST and PSI-BLAST: a new generation of protein database search programs [J].
Altschul, SF ;
Madden, TL ;
Schaffer, AA ;
Zhang, JH ;
Zhang, Z ;
Miller, W ;
Lipman, DJ .
NUCLEIC ACIDS RESEARCH, 1997, 25 (17) :3389-3402
[2]   CAFASP3: The third critical assessment of fully automated structure prediction methods [J].
Fischer, D ;
Rychlewski, L ;
Dunbrack, RL ;
Ortiz, AR ;
Elofsson, A .
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 2003, 53 :503-516
[3]   A MODEL RECOGNITION APPROACH TO THE PREDICTION OF ALL-HELICAL MEMBRANE-PROTEIN STRUCTURE AND TOPOLOGY [J].
JONES, DT ;
TAYLOR, WR ;
THORTON, JM .
BIOCHEMISTRY, 1994, 33 (10) :3038-3049
[4]   GenTHREADER: An efficient and reliable protein fold recognition method for genomic sequences [J].
Jones, DT .
JOURNAL OF MOLECULAR BIOLOGY, 1999, 287 (04) :797-815
[5]   Protein secondary structure prediction based on position-specific scoring matrices [J].
Jones, DT .
JOURNAL OF MOLECULAR BIOLOGY, 1999, 292 (02) :195-202
[6]   A NEW APPROACH TO PROTEIN FOLD RECOGNITION [J].
JONES, DT ;
TAYLOR, WR ;
THORNTON, JM .
NATURE, 1992, 358 (6381) :86-89
[7]   Do transmembrane protein superfolds exist? [J].
Jones, DT .
FEBS LETTERS, 1998, 423 (03) :281-285
[8]   Rapid protein domain assignment from amino acid sequence using predicted secondary structure [J].
Marsden, RL ;
McGuffin, LJ ;
Jones, DT .
PROTEIN SCIENCE, 2002, 11 (12) :2814-2824
[9]   Improvement of the GenTHREADER method for genomic fold recognition [J].
McGuffin, LJ ;
Jones, DT .
BIOINFORMATICS, 2003, 19 (07) :874-881
[10]   The PSIPRED protein structure prediction server [J].
McGuffin, LJ ;
Bryson, K ;
Jones, DT .
BIOINFORMATICS, 2000, 16 (04) :404-405