Primary Cilia Bend LKB1 and mTOR to Their Will

被引：6

作者：

Aznar, Nicolas ^{[2
]}

Billaud, Marc ^{[1
,2
]}

机构：

[1] Univ Grenoble 1, Inst Albert Bonniot, CRI INSERM UJF U823, F-38706 La Tronche, France

[2] Univ Lyon 1, CNRS Mol Genet Signaling & Canc, Ctr Leon Berard, UMR 5201, F-69008 Lyon, France

来源：

DEVELOPMENTAL CELL | 2010年 / 19卷 / 06期

关键词：

DISEASE; INHIBITION; DELETION; PATHWAY; AMPK;

D O I：

10.1016/j.devcel.2010.11.016

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Primary cilia are cell surface organelles that act as sensory antennae for various input signals. In a recent issue of Nature Cell Biology, Boehlke et al. (2010) demonstrate that bending of cilia regulates cell size through a signaling pathway involving the LKB1 and mTOR kinases.

引用

收藏

页码：792 / 794

页数：3

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