Differentiation of Adipose Tissue-Derived Stem Cells into Cardiomyocytes: An Overview

被引:1
作者
Yan, Wenju [1 ,2 ,3 ]
Li, Yan [3 ,4 ]
Li, Gaiqin [5 ]
Yin, Luhua [2 ]
Zhang, Huanyi [2 ]
Yan, Suhua [1 ,3 ,4 ]
机构
[1] Shandong Univ, Cheeloo Coll Med, Jinan 250100, Shandong, Peoples R China
[2] Taian City Cent Hosp, Dept Vasculocardiol, Tai An 271000, Shandong, Peoples R China
[3] Shandong Univ, Shandong Qianfoshan Hosp, Cheeloo Coll Med, Jinan 250100, Shandong, Peoples R China
[4] Shandong First Med Univ, Hosp 1, Jinan 250100, Shandong, Peoples R China
[5] Taian City Cent Hosp, Dept Gastroenterol, Tai An 271000, Shandong, Peoples R China
关键词
Cardiovascular Diseases; Adipose Tissue-Derived Stem Cells (ADSCs); Cardiomyocytes; Differentiation; Cardiac Tissue Engineering; SIGNALING ENHANCES DIFFERENTIATION; STROMAL CELLS; CARDIOVASCULAR-DISEASE; PROGENITOR CELLS; HEART; TRANSPLANTATION; 5-AZACYTIDINE; PATHWAY; INFLAMMATION; DYSFUNCTION;
D O I
10.1166/jbt.2022.2890
中图分类号
Q813 [细胞工程];
学科分类号
摘要
Cardiovascular diseases, including congenital and acquired cardiovascular diseases, impose a severe burden on healthcare systems worldwide. Although bone marrow-derived stem cells (BMSCs) therapy can be an effective therapeutic strategy for the heart disease, relatively low abundance, difficult accessibility, and small tissue volume hinder the clinical usefulness. Adipose tissue-derived stem cells (ADSCs) show similar potential with BMSCs to differentiate into lineages and tissues, such as smooth muscle cells, endothelial cells, and adipocytes, with attractiveness of obtaining adipose tissue easily and repeatedly, and a simple separation procedure. We briefly summarize the current understanding of the cardiomyocytes differentiated from ADSCs.
引用
收藏
页码:427 / 431
页数:5
相关论文
共 50 条
  • [41] Harvesting human adipose tissue-derived adult stem cells: resection versus liposuction
    Schreml, Stephan
    Babilas, Philipp
    Fruth, Sabine
    Orso, Evelyn
    Schmitz, Gerd
    Mueller, Michael B.
    Nerlich, Michael
    Prantl, Lukas
    CYTOTHERAPY, 2009, 11 (07) : 947 - 957
  • [42] Effects of Systemic Transplantation of Adipose Tissue-Derived Stem Cells on Olfactory Epithelium Regeneration
    Kim, Yong Min
    Choi, Young Seok
    Choi, Jin Woong
    Park, Yong Ho
    Koo, Bon Seok
    Roh, Hwan-Jung
    Rha, Ki-Sang
    LARYNGOSCOPE, 2009, 119 (05) : 993 - 999
  • [43] Human adipose tissue-derived stem cells exhibit proliferation potential and spontaneous rhythmic contraction after fusion with neonatal rat cardiomyocytes
    Metzele, Roxana
    Alt, Christopher
    Bai, Xiaowen
    Yan, Yasheng
    Zhang, Zhi
    Pan, Zhizhong
    Coleman, Michael
    Vykoukal, Jody
    Song, Yao-Hua
    Alt, Eckhard
    FASEB JOURNAL, 2011, 25 (03) : 830 - 839
  • [44] Adipose Tissue-Derived Stem Cells Characterization and Potential for Cardiovascular Repair
    Madonna, Rosalinda
    Geng, Yong-Jian
    De Caterina, Raffaele
    ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 2009, 29 (11) : 1723 - 1729
  • [45] Adipose tissue-derived stem cells for cell therapy of airway allergic diseases in mouse
    Jang, Hyeong-Jun
    Cho, Kyu-Sup
    Park, Hee-Young
    Roh, Hwan-Jung
    ACTA HISTOCHEMICA, 2011, 113 (05) : 501 - 507
  • [46] In Vivo Differentiation of Undifferentiated Human Adipose Tissue-Derived Mesenchymal Stem Cells in Critical-Sized Calvarial Bone Defects
    Choi, Jong Woo
    Park, Eun Jung
    Shin, Heung Soo
    Shin, Il Seob
    Ra, Jung Chan
    Koh, Kyung Suk
    ANNALS OF PLASTIC SURGERY, 2014, 72 (02) : 225 - 233
  • [47] Generation of Skin Tissue Using Adipose Tissue-Derived Stem Cells
    Ozpur, Mustafa Aykut
    Guneren, Ethem
    Canter, Halil Ibrahim
    Karaaltin, Mehmet Veli
    Ovali, Ercument
    Yogun, Fatma Nilay
    Baygol, Emre Gonenc
    Kaplan, Suleyman
    PLASTIC AND RECONSTRUCTIVE SURGERY, 2016, 137 (01) : 134 - 143
  • [48] Comparison of bone marrow-vs. adipose tissue-derived mesenchymal stem cells for attenuating liver fibrosis
    Hao, Tianpao
    Chen, Jingfeng
    Zhi, Shaoce
    Zhang, Qiyu
    Chen, Gang
    Yu, Fuxiang
    EXPERIMENTAL AND THERAPEUTIC MEDICINE, 2017, 14 (06) : 5956 - 5964
  • [49] Deducing Insulin-Producing Cells from Goat Adipose Tissue-Derived Mesenchymal Stem Cells
    Dubey, Amit
    Saini, Sikander
    Sharma, Vishal
    Malik, Hrudananda
    Kumar, Dinesh
    De, Arun Kumar
    Bhattacharya, Debasis
    Malakar, Dhruba
    CELLULAR REPROGRAMMING, 2022, 24 (04) : 195 - 203