Differentiation of Adipose Tissue-Derived Stem Cells into Cardiomyocytes: An Overview

被引：1

作者：

Yan, Wenju ^{[1
,2
,3
]}

Li, Yan ^{[3
,4
]}

Li, Gaiqin ^{[5
]}

Yin, Luhua ^{[2
]}

Zhang, Huanyi ^{[2
]}

Yan, Suhua ^{[1
,3
,4
]}

机构：

[1] Shandong Univ, Cheeloo Coll Med, Jinan 250100, Shandong, Peoples R China

[2] Taian City Cent Hosp, Dept Vasculocardiol, Tai An 271000, Shandong, Peoples R China

[3] Shandong Univ, Shandong Qianfoshan Hosp, Cheeloo Coll Med, Jinan 250100, Shandong, Peoples R China

[4] Shandong First Med Univ, Hosp 1, Jinan 250100, Shandong, Peoples R China

[5] Taian City Cent Hosp, Dept Gastroenterol, Tai An 271000, Shandong, Peoples R China

来源：

JOURNAL OF BIOMATERIALS AND TISSUE ENGINEERING | 2022年 / 12卷 / 02期

关键词：

Cardiovascular Diseases; Adipose Tissue-Derived Stem Cells (ADSCs); Cardiomyocytes; Differentiation; Cardiac Tissue Engineering; SIGNALING ENHANCES DIFFERENTIATION; STROMAL CELLS; CARDIOVASCULAR-DISEASE; PROGENITOR CELLS; HEART; TRANSPLANTATION; 5-AZACYTIDINE; PATHWAY; INFLAMMATION; DYSFUNCTION;

D O I：

10.1166/jbt.2022.2890

中图分类号：

Q813 [细胞工程];

学科分类号：

摘要：

Cardiovascular diseases, including congenital and acquired cardiovascular diseases, impose a severe burden on healthcare systems worldwide. Although bone marrow-derived stem cells (BMSCs) therapy can be an effective therapeutic strategy for the heart disease, relatively low abundance, difficult accessibility, and small tissue volume hinder the clinical usefulness. Adipose tissue-derived stem cells (ADSCs) show similar potential with BMSCs to differentiate into lineages and tissues, such as smooth muscle cells, endothelial cells, and adipocytes, with attractiveness of obtaining adipose tissue easily and repeatedly, and a simple separation procedure. We briefly summarize the current understanding of the cardiomyocytes differentiated from ADSCs.

引用

页码：427 / 431

页数：5

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