Cognitive deficits in obsessive-compulsive disorder on tests of frontal lobe functions

被引:44
|
作者
Fenger, MM
Gade, A
Adams, KH
Hansen, ES
Bolwig, TG
Knudsen, GM
机构
[1] Univ Copenhagen, Dept Psychol, DK-1168 Copenhagen, Denmark
[2] Copenhagen Univ Hosp, Dept Neurol, Neurobiol Res Unit, Copenhagen, Denmark
[3] Copenhagen Univ Hosp, Dept Psychiat, Copenhagen, Denmark
关键词
frontal lobe; neuropsychological tests; obsessive-compulsive disorder (OCD); response reversal; set shifting;
D O I
10.1080/08039480510018814
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
Individuals with obsessive-compulsive disorder (OCD) display frontal lobe deficits, but there are inconsistencies between various tests of frontal lobe functions and between the results from different studies. The objective of this work was to characterize frontal lobe dysfunctions in OCD patients. Fifteen patients and 17 control subjects matched for age, sex and intelligence were tested on classic tests of frontal lobe functions [Wisconsin Card Sorting Test (WCST) and tests of fluency], a smell identification test and one computerized test: the Intra/Extra Dimension test. The Intra/Extra Dimension test showed a significant difference between the two groups in reversal of response. The test of Figural fluency showed a significant difference between the two groups in numbers of produced figures. There were no differences on the WCST, verbal fluency and the smell identification test.
引用
收藏
页码:39 / 44
页数:6
相关论文
共 50 条
  • [41] NEUROSURGICAL TREATMENT FOR REFRACTORY OBSESSIVE-COMPULSIVE DISORDER - IMPLICATIONS FOR UNDERSTANDING FRONTAL-LOBE FUNCTION
    MINDUS, P
    RASMUSSEN, SA
    LINDQUIST, C
    JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES, 1994, 6 (04) : 467 - 477
  • [42] Frontal lobe dysfunction in obsessive-compulsive disorder and major depression: a clinical-neuropsychological study
    Cavedini, P
    Ferri, S
    Scarone, S
    Bellodi, L
    PSYCHIATRY RESEARCH, 1998, 78 (1-2) : 21 - 28
  • [43] REDUCED COGNITIVE INHIBITION IN OBSESSIVE-COMPULSIVE DISORDER
    ENRIGHT, SJ
    BEECH, AR
    BRITISH JOURNAL OF CLINICAL PSYCHOLOGY, 1993, 32 : 67 - 74
  • [44] Cognitive inhibition in trichotillomania and obsessive-compulsive disorder
    Bohne, A
    Keuthen, NJ
    Tuschen-Caffier, B
    Wilhelm, S
    BEHAVIOUR RESEARCH AND THERAPY, 2005, 43 (07) : 923 - 942
  • [45] Neuropsychological study of frontal lobe function in psychotropic-naive children with obsessive-compulsive disorder
    Beers, SR
    Rosenberg, DR
    Dick, EL
    Williams, T
    O'Hearn, KM
    Birmaher, B
    Ryan, CM
    AMERICAN JOURNAL OF PSYCHIATRY, 1999, 156 (05): : 777 - 779
  • [46] An Evaluation of Metacognitive Functions in Obsessive-Compulsive Disorder
    Guneysu, Ilker
    Akpinar Asian, Esma
    Batmaz, Sedat
    Guneysu, Seda
    NOROPSIKIYATRI ARSIVI-ARCHIVES OF NEUROPSYCHIATRY, 2025, 62 (01): : 62 - 68
  • [47] Cognitive and neurobiological findings in obsessive-compulsive disorder
    Anderson, KE
    Savage, CR
    PSYCHIATRIC CLINICS OF NORTH AMERICA, 2004, 27 (01) : 37 - +
  • [48] Neuropsychological slowness in obsessive-compulsive disorder: Is it limited to tests assessing executive functions?
    Bucci, P
    Mucci, A
    Piegari, G
    Di Benedetto, R
    Garramone, S
    Galderisi, S
    Maj, M
    EUROPEAN PSYCHIATRY, 2004, 19 : 222S - 223S
  • [49] Comorbidity of obsessive-compulsive disorder with obsessive-compulsive personality disorder: Does it imply a specific subtype of obsessive-compulsive disorder?
    Garyfallos, George
    Katsigiannopoulos, Konstantinos
    Adamopoulou, Aravela
    Papazisis, Georgios
    Karastergiou, Anastasia
    Bozikas, Vasilios P.
    PSYCHIATRY RESEARCH, 2010, 177 (1-2) : 156 - 160
  • [50] Obsessive-compulsive disorder with obsessive-compulsive personality disorder - A case report
    Gudi, A.
    EUROPEAN PSYCHIATRY, 2018, 48 : S359 - S359