Caging the Elephant: Selective Autophagy Tackles Giant Intracellular Protein Crystals

被引:1
|
作者
Habisov, Sabrina [1 ,2 ]
Kirkin, Vladimir [1 ]
机构
[1] Merck KGaA, D-64293 Darmstadt, Germany
[2] Goethe Univ Frankfurt, BMLS Buchmann Inst Mol Life Sci, D-60438 Frankfurt, Germany
关键词
RECEPTORS; UBIQUITIN;
D O I
10.1016/j.molcel.2015.03.022
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
In this issue of Molecular Cell, Tsutsui et al. (2015) show that in vivo protein crystallization may come in handy not only when solving the structure of a protein, but also when studying molecular mechanisms of selective autophagy.
引用
收藏
页码:5 / 7
页数:3
相关论文
共 50 条
  • [1] Intracellular Protein Photoactivation Using Sterically Bulky Caging
    Yamaguchi, Satoshi
    Yamamoto, Kazuho
    Yamamoto, Ryotaro
    Takamori, Satoshi
    Ishiwatari, Akira
    Minamihata, Kosuke
    Nagamune, Teruyuki
    Okamoto, Akimitsu
    CHEMBIOCHEM, 2022, 23 (22)
  • [2] Protein Kinase R Restricts the Intracellular Survival of Mycobacterium tuberculosis by Promoting Selective Autophagy
    Smyth, Robin
    Berton, Stefania
    Rajabalee, Nusrah
    Chan, Therese
    Sun, Jim
    FRONTIERS IN MICROBIOLOGY, 2021, 11
  • [3] Aptamer-Guided Caging for Selective Masking of Protein Domains
    Rohrbach, Falk
    Schaefer, Florian
    Fichte, Manuela A. H.
    Pfeiffer, Franziska
    Mueller, Jens
    Poetzsch, Bernd
    Heckel, Alexander
    Mayer, Guenter
    ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2013, 52 (45) : 11912 - 11915
  • [4] Selective autophagy of intracellular organelles: recent research advances
    Li, Wen
    He, Pengcheng
    Huang, Yuge
    Li, Yi-Fang
    Lu, Jiahong
    Li, Min
    Kurihara, Hiroshi
    Luo, Zhuo
    Meng, Tian
    Onishi, Mashun
    Ma, Changle
    Jiang, Lei
    Hu, Yongquan
    Gong, Qing
    Zhu, Dongxing
    Xu, Yiming
    Liu, Rong
    Liu, Lei
    Yi, Cong
    Zhu, Yushan
    Ma, Ningfang
    Okamoto, Koji
    Xie, Zhiping
    Liu, Jinbao
    He, Rong-Rong
    Feng, Du
    THERANOSTICS, 2021, 11 (01): : 222 - 256
  • [5] Autophagy: a multifaceted intracellular system for bulk and selective recycling
    Li, Faqiang
    Vierstra, Richard D.
    TRENDS IN PLANT SCIENCE, 2012, 17 (09) : 526 - 537
  • [6] The role of autophagy in degradation of intracellular protein aggregates
    Iwata, A
    Kopito, R
    FEBS JOURNAL, 2005, 272 : 398 - 398
  • [7] Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy
    Tannous, Paul
    Zhu, Hongxin
    Johnstone, Janet L.
    Shelton, John M.
    Reynolds, Donald W.
    Soorappan, Raj
    Benjamin, Ivor J.
    Rothermel, Beverly A.
    Hill, Joseph A.
    Reynolds, Donald W.
    CIRCULATION, 2006, 114 (18) : 241 - 241
  • [8] Intracellular Protein Aggregation Is a Proximal Trigger of Cardiomyocyte Autophagy
    Tannous, Paul
    Zhu, Hongxin
    Nemchenko, Andriy
    Berry, Jeff M.
    Johnstone, Janet L.
    Shelton, John M.
    Miller, Francis J., Jr.
    Rothermel, Beverly A.
    Hill, Joseph A.
    CIRCULATION RESEARCH, 2008, 103 (05) : E53 - E53
  • [9] Intracellular protein aggregation is a proximal trigger of cardiomyocyte autophagy
    Tannous, Paul
    Zhu, Hongxin
    Nemchenko, Andriy
    Berry, Jeff M.
    Johnstone, Janet L.
    Shelton, John M.
    Miller, Francis J., Jr.
    Rothermel, Beverly A.
    Hill, Joseph A.
    CIRCULATION, 2008, 117 (24) : 3070 - 3078