Involvement of cholesterol, calcium and progesterone in the induction of capacitation and acrosome reaction of mammalian spermatozoa

被引:85
作者
Witte, Tanja Semira [1 ]
Schaefer-Somi, Sabine [1 ]
机构
[1] Univ Vet Sci, Ctr Artificial Inseminat & Embryo Transfer, A-1210 Vienna, Austria
关键词
dog; cholesterol; calcium; progesterone; acrosome reaction; capacitation;
D O I
10.1016/j.anireprosci.2007.07.007
中图分类号
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号
0905 ;
摘要
The aim of this paper was to review the effects of some important substances involved in the induction of sperm plasma membrane changes referred to as acrosome reaction, namely cholesterol (C), calcium (Ca2+) and progesterone (P-4). For this purpose, mechanisms of capacitation and acrosome reaction (AR) as well as the processes, C, Ca2+ and P-4 are involved in, are described. Subsequently, to get a better insight into possible beneficial and detrimental effects on sperm function, the occurrence of these molecules in semen extenders is discussed. (C) 2007 Elsevier B.V. All rights reserved.
引用
收藏
页码:181 / 193
页数:13
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