The value of chlamydial antibody level for predicting tubal blockage among women undergoing hysterosalpingography in Lagos, Nigeria

被引：8

作者：

Olaleye, Olalekan ^{[1
]}

Olamijulo, Joseph A. ^{[2
]}

机构：

[1] Lagoon Hosp, Dept Obstet & Gynecol, Lagos, Nigeria

[2] Univ Lagos, Dept Obstet & Gynecol, Coll Med, Lagos, Nigeria

来源：

INTERNATIONAL JOURNAL OF GYNECOLOGY & OBSTETRICS | 2016年 / 134卷 / 01期

关键词：

Chlamydial antibody; Chlamydia trachomatis; Hysterosalpingography; Pelvic inflammatory disease; Sexually transmitted infection; Tubal blockage; Tubal infertility; PATIENT DATA METAANALYSIS; TRACHOMATIS-INFECTION; SUBFERTILE WOMEN; INFERTILITY; DIAGNOSIS; PATHOLOGY; SEROLOGY;

D O I：

10.1016/j.ijgo.2015.12.009

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective: To determine the prevalence of Chlamydia trachomatis infection among Nigerian women undergoing hysterosalpingography (HSG) and to identify any correlation between chlamydial antibody levels and a diagnosis of tubal disease. Methods: A prospective cross-sectional study was conducted from January 1 to June 30, 2013, among women scheduled to undergo HSG in the radiology department of Lagos University Teaching Hospital, Nigeria. Endocervical swabs and serum samples were collected to assess the levels of chlamydial antigen and antibody, respectively. Results: Among 150 participants, 83 (55.3%) had bilateral tubal patency and 67 (44.7%) had tubal disease. Overall, 53 (35.3%) women had positive test results for chlamydial antibodies; however, none of the participants tested positive for chlamydial antigen. Women with tubal disease were more likely to test positive for chlamydial antibodies (n = 44 [65.7%]) than were those whose test results were negative (n = 9 [10.8%]; P < 0.001). The sensitivity and specificity of chlamydial antibody testing to predict tubal disease diagnosed by HSG were 66% and 89%, respectively. Conclusion: The presence of chlamydial antibodies was quantitatively related to the likelihood of HSG-diagnosed tubal disease. (C) 2016 Published by Elsevier Ireland Ltd.

引用

页码：33 / 36

页数：4

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