Dedifferentiated chondrosarcoma of the middle finger arising from a solitary enchondroma: A case report

被引：4

作者：

Yonezawa, Hirotaka ^{[1
]}

Yamamoto, Norio ^{[1
]}

Hayashi, Katsuhiro ^{[1
]}

Takeuchi, Akihiko ^{[1
]}

Miwa, Shinji ^{[1
]}

Igarashi, Kentaro ^{[1
]}

Morinaga, Sei ^{[1
]}

Asano, Yohei ^{[1
]}

Saito, Shiro ^{[1
]}

Tome, Yasunori ^{[2
]}

Ikeda, Hiroko ^{[3
]}

Nojima, Takayuki ^{[1
,3
]}

Tsuchiya, Hiroyuki ^{[1
]}

机构：

[1] Kanazawa Univ, Grad Sch Med Sci, Dept Orthopaed Surg, 13-1 Takara Machi, Kanazawa, Ishikawa 9208641, Japan

[2] Univ Ryukyus, Grad Sch Med, Dept Orthoped Surg, Nishihara, Okinawa 9030215, Japan

[3] Kanazawa Univ Hosp, Dept Diagnost Pathol, Kanazawa, Ishikawa 9208641, Japan

来源：

WORLD JOURNAL OF CLINICAL CASES | 2022年 / 10卷 / 10期

关键词：

Dedifferentiated chondrosarcoma; Enchondroma; Finger; Phalanx; Ray amputation; Case report; COMPONENT; HAND;

D O I：

10.12998/wjcc.v10.i10.3297

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

BACKGROUND Dedifferentiated chondrosarcoma (DDCS) accounts for 10% of all chondrosarcomas and has the poorest outcome, with a 5-year survival rate of 7%-25%. DDCS commonly occurs in the femur and pelvis, whereas DDCS of the finger is extremely rare. Furthermore, the histological findings of preexisting solitary enchondroma samples are important and valuable for diagnosing malignant transformations. CASE SUMMARY We report our experience with DDCS in the proximal phalanx of the left middle finger of an 87-year-old woman. She had undergone surgery for enchondroma, with curettage and artificial bone grafting, 11 years ago, in the same location. Several years after the primary surgery, the left middle finger gradually started to enlarge, and the growth speed increased in the past year. Plain radiographs showed an expansive osteolytic lesion with calcifications and residual grafting material. Owing to the suspicion of malignancy, we performed ray amputation. Histological findings revealed an abrupt transition between the low-grade chondrosarcoma and dedifferentiated sarcoma components. The dedifferentiated components showed the features of a high-grade undifferentiated pleomorphic sarcoma. The patient was diagnosed with DDCS arising from a preexisting enchondroma. She had no local recurrence or distant metastasis and died of pneumonia 6 years and 10 months after the second surgery. CONCLUSION The histological findings of a precursor lesion showed a typical enchondroma, suggesting that DDCS can arise from enchondroma.

引用

页码：3297 / 3305

页数：9

共 24 条

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