Impact of radiotherapy on implant-based prosthetic rehabilitation in patients with head and neck cancer: A prospective observational study on implant survival and quality of life-Preliminary results

被引：19

作者：

Ettl, Tobias ^{[1
]}

Weindler, Janet ^{[1
]}

Gosau, Martin ^{[2
]}

Mueller, Steffen ^{[1
]}

Hautmann, Matthias ^{[3
]}

Zeman, Florian ^{[4
]}

Koller, Michael ^{[4
]}

Papavasileiou, Dimitrios ^{[5
]}

Buergers, Ralf ^{[6
]}

Driemel, Oliver ^{[7
,8
]}

Schneider, Isabel ^{[1
]}

Klingelhoeffer, Christoph ^{[1
]}

Meier, Johannes ^{[1
]}

Wahlmann, Ulrich ^{[1
]}

Reichert, Torsten E. ^{[1
]}

机构：

[1] Univ Med Ctr Regensburg, Dept Oral & Maxillofacial Surg, Franz Josef Strauss Allee 11, D-93053 Regensburg, Germany

[2] Nuremberg Hosp, Dept Oral & Maxillofacial Surg, Breslauer Str 201, D-90471 Nurnberg, Germany

[3] Univ Med Ctr Regensburg, Dept Radiotherapy, Franz Josef Strauss Allee 11, D-93053 Regensburg, Germany

[4] Univ Med Ctr Regensburg, Ctr Clin Studies, Franz Josef Strauss Allee 11, D-93053 Regensburg, Germany

[5] Univ Med Ctr Regensburg, Dept Prosthodont, Franz Josef Strauss Allee 11, D-93053 Regensburg, Germany

[6] Univ Hosp Gottingen, Dept Prosthodont, Robert Koch Str 40, D-37075 Gottingen, Germany

[7] Univ Med Ctr Rostock, Dept Oral & Maxillofacial Surg, Schillingallee 35, D-18057 Rostock, Germany

[8] Steinburgsgang 2, D-26789 Leer, Germany

来源：

JOURNAL OF CRANIO-MAXILLOFACIAL SURGERY | 2016年 / 44卷 / 09期

关键词：

Head and neck cancer; Radiotherapy; Prosthetic rehabilitation; Implant success; Quality of life; FOLLOW-UP PERIOD; ORAL-CANCER; OF-LIFE; DENTAL IMPLANTS; IRRADIATED PATIENTS; CLINICAL-EVALUATION; ENDOSTEAL IMPLANTS; HEALTH; THERAPY; RECONSTRUCTION;

D O I：

10.1016/j.jcms.2016.07.016

中图分类号：

R78 [口腔科学];

学科分类号：

1003 ;

摘要：

Purpose: To study implant-based prosthetic rehabilitation of head and neck cancer patients with focus on implant survival and quality of life. Materials and methods: The prospective observational study presents preliminary results of 29 edentulous head neck cancer patients (20 patients after radiotherapy) with 165 OsseoSpeed implants. Implant success after 1-year follow-up was evaluated by means of the Albrektsson criteria. Quality of life was analysed with the EORTC QLQ-C30, QLQ-H&N35, and OHIP 14 questionnaires. Results: The overall implant survival rate after 1 year was 95.2% (157/165). Implant success measured by the Albrektsson criteria showed a lower success rate of 86.7% (143/165), mainly because of peri-implant marginal bone loss with a mean of 0.8 mm after 1 year. Xerostomia (p = 0.008), implant insertion within the radiation target volume (p = 0.09), implantation in transplanted bone (p = 0.05), and smoking (p = 0.041) were the main reasons for implant failure, followed by D4 bone quality, maxillary implant site, and insufficient primary stability. Speaking, swallowing, eating, as well as social integration and individual self-confidence had considerably improved 1 year after denture placement compared to before treatment. Conclusion: Implant-based prosthetic rehabilitation of head and neck cancer patients is possible at a calculable risk and significantly improves patients' quality of life. (C) 2016 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.

引用

页码：1453 / 1462

页数：10

共 44 条

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