Utilisation of tracheostomy in patients with COVID-19 in England: Patient characteristics, timing and outcomes

被引:3
作者
Navaratnam, Annakan, V [1 ]
Gray, William K. [1 ]
Wall, Josh [1 ]
Takhar, Arun [2 ]
Day, Jamie [1 ]
Tatla, Taranjit [3 ]
Batchelor, Anna [1 ]
Swart, Michael [1 ]
Snowden, Christopher [1 ]
Marshall, Andrew [1 ]
Briggs, Tim W. R. [1 ]
机构
[1] NHS England & NHS Improvement, Getting It Right First Time Programme, Skipton House,80 London Rd, London SE1 6LH, England
[2] Guys & St Thomas NHS Fdn Trust, London, England
[3] London North West Hosp NHS Trust, London, England
关键词
COVID-19; intubation; mechanical ventilation; SARS-CoV2; tracheostomy;
D O I
10.1111/coa.13913
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Objectives We aimed to characterise the use of tracheostomy procedures for all COVID-19 critical care patients in England and to understand how patient factors and timing of tracheostomy affected outcomes. Design A retrospective observational study using exploratory analysis of hospital administrative data. Setting All 500 National Health Service hospitals in England. Participants All hospitalised COVID-19 patients aged >= 18 years in England between 1 March and 31 October 2020 were included. Main outcomes and measures This was a retrospective exploratory analysis using the Hospital Episode Statistics administrative data set. Multilevel modelling was used to explore the relationship between demographic factors, comorbidity and use of tracheostomy and the association between tracheostomy use, tracheostomy timing and the outcomes. Results In total, 2200 hospitalised COVID-19 patients had a tracheostomy. Tracheostomy utilisation varied across the study period, peaking in April-June 2020. In multivariable modelling, for those admitted to critical care, tracheostomy was most common in those aged 40-79 years, in males and in people of Black and Asian ethnic groups and those with a history of cerebrovascular disease. In critical care patients, tracheostomy was associated with lower odds of mortality (OR: 0.514 [95% CI 0.443 to 0.596], but greater length of stay OR: 41.143 [95% CI 30.979 to 54.642]). In patients that survived, earlier timing of tracheostomy (<= 14 days post admission to critical care) was significantly associated with shorter length of stay. Conclusions Tracheostomy is safe and advantageous for critical care COVID-19 patients. Early tracheostomy may be associated with better outcomes, such as shorter length of stay, compared to late tracheostomy.
引用
收藏
页码:424 / 432
页数:9
相关论文
共 19 条
[2]   Safety and 30-day outcomes of tracheostomy for COVID-19: a prospective observational cohort study [J].
Breik, Omar ;
Sharma, Neil ;
Dawson, Camilla ;
Bangash, Mansoor N. ;
Idle, Matthew ;
Isherwood, Peter ;
Jennings, Christopher ;
Keene, Damian ;
Manji, Mav ;
Martin, Tim ;
Moss, Rob ;
Murphy, Nick ;
Parekh, Dhruv ;
Parmar, Sat ;
Patel, Jaimin ;
Pracy, Paul ;
Praveen, Prav ;
Richardson, Carla ;
Richter, Alex ;
Sachdeva, Rajneesh ;
Shields, Adrian ;
Siddiq, Somiah ;
Smart, Simon ;
Tasker, Laura ;
Nankivell, Paul .
BRITISH JOURNAL OF ANAESTHESIA, 2020, 125 (06) :872-879
[3]   A NEW METHOD OF CLASSIFYING PROGNOSTIC CO-MORBIDITY IN LONGITUDINAL-STUDIES - DEVELOPMENT AND VALIDATION [J].
CHARLSON, ME ;
POMPEI, P ;
ALES, KL ;
MACKENZIE, CR .
JOURNAL OF CHRONIC DISEASES, 1987, 40 (05) :373-383
[4]  
Cummings Matthew J, 2020, medRxiv, DOI [10.1016/S0140-6736(20)31189-2, 10.1101/2020.04.15.20067157]
[5]   Features of 20133 UK patients in hospital with covid-19 using the ISARIC WHO Clinical Characterisation Protocol: prospective observational cohort study [J].
Docherty, Annemarie B. ;
Harrison, Ewen M. ;
Green, Christopher A. ;
Hardwick, Hayley E. ;
Pius, Riinu ;
Norman, Lisa ;
Holden, Karl A. ;
Read, Jonathan M. ;
Dondelinger, Frank ;
Carson, Gail ;
Merson, Laura ;
Lee, James ;
Plotkin, Daniel ;
Sigfrid, Louise ;
Halpin, Sophie ;
Jackson, Clare ;
Gamble, Carrol ;
Horby, Peter W. ;
Nguyen-Van-Tam, Jonathan S. ;
Ho, Antonia ;
Russell, Clark D. ;
Dunning, Jake ;
Openshaw, Peter Jm ;
Baillie, J. Kenneth ;
Semple, Malcolm G. .
BMJ-BRITISH MEDICAL JOURNAL, 2020, 369
[6]   Safety Recommendations for Evaluation and Surgery of the Head and Neck During the COVID-19 Pandemic [J].
Givi, Babak ;
Schiff, Bradley A. ;
Chinn, Steven B. ;
Clayburgh, Daniel ;
Iyer, N. Gopalakrishna ;
Jalisi, Scharukh ;
Moore, Michael G. ;
Nathan, Cherie-Ann ;
Orloff, Lisa A. ;
O'Neill, James P. ;
Parker, Noah ;
Zender, Chad ;
Morris, Luc G. T. ;
Davies, Louise .
JAMA OTOLARYNGOLOGY-HEAD & NECK SURGERY, 2020, 146 (06) :579-584
[7]   Case characteristics, resource use, and outcomes of 10 021 patients with COVID-19 admitted to 920 German hospitals: an observational study [J].
Karagiannidis, Christian ;
Mostert, Carina ;
Hentschker, Corinna ;
Voshaar, Thomas ;
Malzahn, Jurgen ;
Schillinger, Gerhard ;
Klauber, Juergen ;
Janssens, Uwe ;
Marx, Gernot ;
Weber-Carstens, Steffen ;
Kluge, Stefan ;
Pfeifer, Michael ;
Grabenhenrich, Linus ;
Welte, Tobias ;
Busse, Reinhard .
LANCET RESPIRATORY MEDICINE, 2020, 8 (09) :853-862
[8]   Use of Tracheostomy During the COVID-19 Pandemic American College of Chest Physicians/American Association for Bronchology and Interventional Pulmonology/Association of Interventional Pulmonology Program Directors Expert Panel Report [J].
Lamb, Carla R. ;
Desai, Neeraj R. ;
Angel, Luis ;
Chaddha, Udit ;
Sachdeva, Ashutosh ;
Sethi, Sonali ;
Bencheqroun, Hassan ;
Mehta, Hiren ;
Akulian, Jason ;
Argento, A. Christine ;
Diaz-Mendoza, Javier ;
Musani, Ali ;
Murgu, Septimiu .
CHEST, 2020, 158 (04) :1499-1514
[9]   Risk Factors for Posttracheostomy Tracheal Stenosis [J].
Li, Michael ;
Yiu, Yin ;
Merrill, Tyler ;
Yildiz, Vedat ;
deSilva, Brad ;
Matrka, Laura .
OTOLARYNGOLOGY-HEAD AND NECK SURGERY, 2018, 159 (04) :698-704
[10]   Tracheostomy in the COVID-19 era: global and multidisciplinary guidance [J].
McGrath, Brendan A. ;
Brenner, Michael J. ;
Warrillow, Stephen J. ;
Pandian, Vinciya ;
Arora, Asit ;
Cameron, Tanis S. ;
Anon, Jose Manuel ;
Martinez, Gonzalo Hernandez ;
Truog, Robert D. ;
Block, Susan D. ;
Lui, Grace C. Y. ;
McDonald, Christine ;
Rassekh, Christopher H. ;
Atkins, Joshua ;
Qiang, Li ;
Vergez, Sebastien ;
Dulguerov, Pavel ;
Zenk, Johannes ;
Antonelli, Massimo ;
Pelosi, Paolo ;
Walsh, Brian K. ;
Ward, Erin ;
Shang, You ;
Gasparini, Stefano ;
Donati, Abele ;
Singer, Mervyn ;
Openshaw, Peter J. M. ;
Tolley, Neil ;
Markel, Howard ;
Feller-Kopman, David J. .
LANCET RESPIRATORY MEDICINE, 2020, 8 (07) :717-725