Novel ruthenium-catalyzed cleavage of allyl protecting group in lactams

被引：34

作者：

Alcaide, B ^{[1
]}

Almendros, P

Alonso, JM

机构：

[1] Univ Complutense Madrid, Fac Ciencias Quim, Dept Quim Organ 1, E-28040 Madrid, Spain

[2] CSIC, Inst Quim Organ Gen, E-28006 Madrid, Spain

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 48期

关键词：

lactams; ruthenium; catalytic; allyl cleavage;

D O I：

10.1016/j.tetlet.2003.09.165

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A convenient and general method of synthesis of NH-lactams via Grubbs' carbene promoted isomerization of the respective N-allyl lactams followed by RuCl3-catalyzed enamide cleavage has been developed. (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：8693 / 8695

页数：3

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