Endothelial Keratoplasty: A Revolution in Evolution

被引：136

作者：

Anshu, Arundhati ^{[1
,2
]}

Price, Marianne O. ^{[1
]}

Tan, Donald T. H. ^{[3
,4
,5
]}

Price, Francis W., Jr. ^{[2
]}

机构：

[1] Cornea Res Fdn Amer, Indianapolis, IN 46260 USA

[2] Price Vis Grp, Indianapolis, IN USA

[3] Singapore Natl Eye Ctr, Singapore, Singapore

[4] Singapore Eye Res Inst, Singapore, Singapore

[5] Natl Univ Singapore, Dept Ophthalmol, Yong Loo Lin Sch Med, Singapore 117548, Singapore

来源：

SURVEY OF OPHTHALMOLOGY | 2012年 / 57卷 / 03期

关键词：

Endothelial keratoplasty; Descemet's stripping endothelial keratoplasty; Descemet's membrane endothelial keratoplasty; posterior lamellar keratoplasty; DMEK; DSAEK; DMAEK; POSTERIOR LAMELLAR KERATOPLASTY; FAILED PENETRATING KERATOPLASTY; PRIMARY GRAFT FAILURE; DESCEMET-MEMBRANE; CELL LOSS; INTRAOCULAR-PRESSURE; CATARACT FORMATION; VISUAL-ACUITY; RISK-FACTORS; SUPRACHOROIDAL HEMORRHAGE;

D O I：

10.1016/j.survophthal.2011.10.005

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Endothelial keratoplasty (EK) is continually evolving both in surgical technique and clinical outcomes. Descemet's stripping endothelial keratoplasty (DSEK) has replaced penetrating keratoplasty (PK) as the treatment of choice for corneal endothelial dysfunction. It is safe and predictable and offers early visual rehabilitation. Newer iterations include Descemet's membrane endothelial keratoplasty, Descemet's membrane automated endothelial keratoplasty, and other hybrid techniques. Early data on these newer EK techniques suggests that they provide significantly better visual outcomes compared to DSEK. Initial 5-year survival data indicates that EK is at least comparable to PK, and more widespread survival data is anticipated. Further work is needed to simultaneously optimize visual outcomes, refractive predictability, and endothelial cell survival, as well as surgical techniques of donor preparation and insertion. (Surv Ophthalmol 57:236-252, 2012. (C) 2012 Elsevier Inc. All rights reserved.)

引用

页码：236 / 252

页数：17

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