Efficient correction of hemoglobinopathy-causing mutations by homologous recombination in integration-free patient iPSCs

被引：55

作者：

Li, Mo ^{[1
]}

Suzuki, Keiichiro ^{[1
]}

Qu, Jing ^{[1
]}

Saini, Preeti ^{[1
]}

Dubova, Ilir ^{[1
]}

Yi, Fei ^{[1
]}

Lee, Jungmin ^{[1
]}

Sancho-Martinez, Ignacio ^{[1
]}

Liu, Guang-Hui ^{[1
]}

Izpisua Belmonte, Juan Carlos ^{[1
,2
]}

机构：

[1] Salk Inst Biol Studies, La Jolla, CA 92037 USA

[2] Ctr Regenerat Med Barcelona, Barcelona 08003, Spain

来源：

CELL RESEARCH | 2011年 / 21卷 / 12期

关键词：

PLURIPOTENT STEM-CELLS; ZINC-FINGER NUCLEASES; GENETIC CORRECTION; DISEASE; MOUSE;

D O I：

10.1038/cr.2011.186

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

引用

页码：1740 / 1744

页数：5

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