Microwave-assisted synthesis of 1,3,4-thiadiazole Schiff base derivatives

被引：7
作者：
Hu, Jun [1 ]
Sun, Jianguang [2 ]
Zhou, Taoyu [1 ]
Xu, Yanhua [1 ]
机构：
[1] Nanjing Univ Technol, Coll Environm, Jiangsu Key Lab Ind Water Conservat & Emiss Reduc, Nanjing 210009, Peoples R China
[2] Huaiyin Inst Technol, Fac Foreign Languages, Huaian 223003, Peoples R China
来源：
JOURNAL OF CHEMICAL RESEARCH | 2011年 / 08期
关键词：
1,3,4-thiadiazole; Schiff base; microwave-assisted synthesis;
D O I：
10.3184/174751911X13128202305728
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A rapid and efficient microwave-assisted synthesis method for the preparation of 1,3,4-thiadiazole Schiff base derivatives is described. These 1,3,4-thiadiazole Schiff bases (5a-h) were identified by IR, H-1 NMR, elemental analyses. The target compounds were performed in a shorter reaction time compared with conventional heating methods.
引用
收藏
页码：442 / 443
页数：2
相关论文
共 19 条
  • [1] Synthesis and antimicrobial evaluation of some fused heterocyclic [1,2,4]triazolo [3,4-b][1,3,4]thiadiazole derivatives
    Almajan, Gabriela Laura
    Barbuceanu, Stefania-Felicia
    Bancescu, Gabriela
    Saramet, Ioana
    Saramet, Gabriel
    Draghici, Constantin
    [J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2010, 45 (12) : 6139 - 6146
  • [2] Chen CZ, 1999, CHEM COMMUN, P1585
  • [3] Synthesis and fungicidal activity against Rhizoctonia solani of 2-alkyl (alkylthio)-5-pyrazolyl-1,3,4-oxadiazoles (thiadiazoles)
    Chen, HS
    Li, ZM
    Han, YF
    [J]. JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 2000, 48 (11) : 5312 - 5315
  • [4] The structures of some ortho-hydroxy Schiff base ligands
    Fernández-G, JM
    del Rio-Portilla, F
    Quiroz-García, B
    Toscano, RA
    Salcedo, R
    [J]. JOURNAL OF MOLECULAR STRUCTURE, 2001, 561 (1-3) : 197 - 207
  • [5] Antifungal properties of Schiff bases of chitosan, N-substituted chitosan and quaternized chitosan
    Guo, Zhanyong
    Xing, Ronge
    Liu, Song
    Zhong, Zhimei
    Ji, Xia
    Wang, Lin
    Li, Pengcheng
    [J]. CARBOHYDRATE RESEARCH, 2007, 342 (10) : 1329 - 1332
  • [6] (E)-5-(3,5-Dimethylphenyl)-N-[4-(methylsulfanyl)benzylidene]-1,3,4-thiadiazol-2-amine
    Hu, Jun
    Ji, Jin-xiu
    Zhou, Ying
    Wang, Ji-kui
    Xu, Yan-hua
    [J]. ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2010, 66 : O410 - U2924
  • [7] Synthesis and biological evaluation of 3,6-disubstituted [1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives as a novel class of potential anti-tumor agents
    Ibrahim, D. A.
    [J]. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 2009, 44 (07) : 2776 - 2781
  • [8] Imran Muhammad, 2007, Turkish Journal of Biology, V31, P67
  • [9] The impact of microwave synthesis on drug discovery
    Kappe, CO
    Dallinger, D
    [J]. NATURE REVIEWS DRUG DISCOVERY, 2006, 5 (01) : 51 - 63
  • [10] Synthesis and antituberculosis activity of new N-phenyl-N′-[4-(5-alkyl/arylamino-1,3,4-thiadiazole-2-yl)phenyl]thioureas
    Karakus, S
    Rollas, S
    [J]. FARMACO, 2002, 57 (07): : 577 - 581
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