Development and validation of a prediction model of deep venous thrombosis for patients with acute poisoning following hemoperfusion: a retrospective analysis

被引：2

作者：

Li, Xiuqin ^{[1
,2
]}

Liu, Jing ^{[2
]}

Cui, Siqi ^{[3
,4
]}

Jian, Tianzi ^{[3
,5
]}

Ma, Shuang ^{[2
,3
]}

Shi, Longke ^{[3
,4
]}

Lin, Ying ^{[1
,2
]}

Zhang, Juan ^{[2
,3
]}

Zheng, Yingying ^{[2
,3
]}

Zhang, Yanxia ^{[2
,3
]}

Jian, Xiangdong ^{[3
,4
]}

Luan, Xiaorong ^{[2
,6
]}

Kan, Baotian ^{[1
,2
]}

机构：

[1] Shandong Univ, Qilu Hosp, Cheeloo Coll Med, Dept Geriatr Med, 107 Rd Wenhuaxi, Jinan 250012, Shandong, Peoples R China

[2] Shandong Univ, Nursing Theory & Practice Innovat Res Ctr, Jinan 250012, Shandong, Peoples R China

[3] Shandong Univ, Qilu Hosp, Cheeloo Coll Med, Dept Poisoning & Occupat Dis,Emergency Med, Jinan 250012, Shandong, Peoples R China

[4] Shandong Univ, Cheeloo Coll Med, Sch Publ Hlth, Jinan 250012, Shandong, Peoples R China

[5] Shandong Univ, Qilu Hosp, Cheeloo Coll Med, Dept Digest Internal Med, Jinan 250012, Shandong, Peoples R China

[6] Shandong Univ, Qilu Hosp, Cheeloo Coll Med, Dept Nursing, Jinan 250012, Shandong, Peoples R China

来源：

JOURNAL OF INTERNATIONAL MEDICAL RESEARCH | 2022年 / 50卷 / 04期

关键词：

Deep venous thrombosis; hemoperfusion; poisoning; prediction model; thrombosis; risk assessment; VEIN-THROMBOSIS; HOSPITALIZED-PATIENTS; RISK; BURDEN;

D O I：

10.1177/03000605221089779

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Objective To develop and confirm an individualized predictive model to ascertain the probability of deep venous thrombosis in patients with acute poisoning after undergoing hemoperfusion. Methods Three hundred eleven patients with acute poisoning who were admitted to a hospital in China between October 2017 and February 2019 were included in the development group. Eighty patients with acute poisoning who were admitted between February and May 2019 were included in the validation group. The independent risk factors for deep venous thrombosis were examined. An individualized predictive model was developed using regression coefficients. Results The number of catheter indwelling days, having a catheter while being transported, elevated serum homocysteine concentrations, and dyslipidemia were independent risk factors for deep venous thrombosis following hemoperfusion in patients with acute poisoning. The areas under the receiver operating characteristic curve of the development and validation groups were 0.713 and 0.702, respectively, which suggested that the prediction model had good discrimination capacity. The calibration belts of the two groups were ideal. Conclusions Our prediction model has a moderate predictive effect for the occurrence of deep venous thrombosis in patients with acute poisoning. In clinical practice, this model could be combined with a common thrombosis risk assessment model.

引用

页数：13

共 25 条

[1] Obesity: risk of venous thrombosis and the interaction with coagulation factor levels and oral contraceptive use [J].