Synthesis of 1,2,3-triazoles by cycloadditions of azides with enol ethers

被引：34

作者：

Roque, DR ^{[1
]}

Neill, JL ^{[1
]}

Antoon, JW ^{[1
]}

Stevens, EP ^{[1
]}

机构：

[1] Davidson Coll, Dept Chem, Davidson, NC 28035 USA

来源：

SYNTHESIS-STUTTGART | 2005年 / 15期

关键词：

azides; cycloadditions; heterocycles; nitrogen; regioselectivity;

D O I：

10.1055/s-2005-872116

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

1,2,3-Triazoles were prepared in good to modest yields by cycloaddition of alkyl azides onto enol ethers under solventless conditions. The reaction can access ring-fused triazoles that are unavailable by azide-alkyne cycloadditions and is easily scalable. The 1,2,3-triazole products bear functionality that may be readily derivatized.

引用

页码：2497 / 2502

页数：6

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