Antigliadin antibodies in Huntington's disease

被引：36

作者：

Bushara, KO

Nance, M

Gomez, CM

机构：

[1] Minneapolis VA Med Ctr, Serv Neurol, Minneapolis, MN 55417 USA

[2] Univ Minnesota, Dept Neurol, Minneapolis, MN 55455 USA

[3] Hennepin Cty Med Ctr, Dept Neurol, Minneapolis, MN 55415 USA

来源：

NEUROLOGY | 2004年 / 62卷 / 01期

关键词：

D O I：

10.1212/WNL.62.1.132

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The relevance of gluten sensitivity in sporadic and hereditary ataxia pathogenesis is unclear. The authors found high antigliadin antibody titers in 23 of 52 (44%) patients with Huntington's disease (HD), suggesting a previously unrecognized association between HD and gluten sensitivity. The results further question "gluten ataxia" as a distinct disease entity and raise the possibility that antigliadin antibodies in ataxia and other neurodegenerative diseases may be an epiphenomenon, the mechanisms of which remain to be investigated.

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页码：132 / 133

页数：2

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