Abnormally activated signaling pathways as potential therapeutic targets, and diagnostic biomarkers in the management of small-cell lung cancers - A review

被引:0
作者
Zhang, Lihai [1 ]
Dai, Longxia [1 ]
Xiao, Jian [1 ]
He, Bixiu [1 ]
机构
[1] Cent South Univ, Xiangya Hosp, Dept Elderly Resp, Changsha 410008, Peoples R China
关键词
Small cell lung cancer (SCLC); Signaling pathway; Biomarker; Lung cancer; Chemotherapy; Radiotherapy; Immunotherapy;
D O I
10.4314/tjpr.v20i12.30
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Small-cell lung cancer (SCLC) has relatively aggressive spread characteristics and a poor prognosis. Current treatment methods include surgery, chemotherapy, radiotherapy, and immunotherapy. However, the prognosis remains poor. This article summarizes the related signaling pathways and factors that may be used as therapeutic targets and early diagnostic biomarkers in the pathogenesis of SCLC. Furthermore, this study provides a theoretical reference for the clinical treatment of SCLC.
引用
收藏
页码:2675 / 2679
页数:5
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