Evaluation of the TB Ag MPT64 Rapid test for the identification of Mycobacterium tuberculosis complex

被引:16
作者
Martin, A. [1 ]
Bombeeck, D. [1 ]
Mulders, W. [1 ]
Fissette, K. [1 ]
De Rijk, P. [1 ]
Palomino, J. C. [1 ]
机构
[1] Inst Trop Med, Mycobacteriol Unit, B-2000 Antwerp, Belgium
关键词
tuberculosis; nitrate reductase; MGIT; 960; drug resistance; CAPILIA TB; KIT;
D O I
10.5588/ijtld.10.0474
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Rapid identification of Mycobacterium tuberculosis complex in cultured samples is important for starting appropriate treatment. We evaluated the performance of the TB Ag MPT64 Rapid test directly from 131 BACTEC (TM) MGIT (TM) 960 culture-positive samples: 113 were identified as M. tuberculosis complex and 18 as non-tuberculous mycobacteria. The sensitivity and specificity of the TB Ag MPT64 Rapid test were respectively 96.5% and 100% compared to the polymerase chain reaction. The overall concordance of the TB Ag MPT64 Rapid test was 969%. The TB Ag MPT64 Rapid test is easy, sensitive, and does not require a high level of skill or specific equipment.
引用
收藏
页码:703 / 705
页数:3
相关论文
共 12 条
[1]   PROTEINS RELEASED FROM MYCOBACTERIUM-TUBERCULOSIS DURING GROWTH [J].
ANDERSEN, P ;
ASKGAARD, D ;
LJUNGQVIST, L ;
BENNEDSEN, J ;
HERON, I .
INFECTION AND IMMUNITY, 1991, 59 (06) :1905-1910
[2]  
BODDINGHAUS B, 1990, J CLIN MICROBIOL, V28, P1751
[3]  
*FDN INN NEW DIAGN, 2010, FIND PRIC BACTEC MGI
[4]   Mutations including IS6110 insertion in the gene encoding the MPB64 protein of capilia TB-negative Mycobacterium tuberculosis isolates [J].
Hirano, K ;
Aono, A ;
Takahashi, M ;
Abe, C .
JOURNAL OF CLINICAL MICROBIOLOGY, 2004, 42 (01) :390-392
[5]  
Ismail NA, 2009, INT J TUBERC LUNG D, V13, P1045
[6]  
Kent P. T, 1985, PUBLIC HLTH MYCOBACT
[7]   Diagnostic performance and costs of Capilia TB for Mycobacterium tuberculosis complex identification from broth-based culture in Bangkok, Thailand [J].
Ngamlert, Keerataya ;
Sinthuwattanawibool, Chalinthorn ;
McCarthy, Kimberly D. ;
Sohn, Hojoon ;
Starks, Angela ;
Kanjanamongkolsiri, Photjanart ;
Anek-vorapong, Rapeepan ;
Tasaneeyapan, Theerawit ;
Monkongdee, Patama ;
Diem, Lois ;
Varma, Jay K. .
TROPICAL MEDICINE & INTERNATIONAL HEALTH, 2009, 14 (07) :748-753
[8]   Evaluation of an Immunochromatographic Assay Kit for Rapid Identification of Mycobacterium tuberculosis Complex in Clinical Isolates [J].
Park, Mi Young ;
Kim, Young Jin ;
Hwang, Sang Hyun ;
Kim, Hyoung Hoi ;
Lee, Eun Yup ;
Jeong, Seok Hoon ;
Chang, Chulhun L. .
JOURNAL OF CLINICAL MICROBIOLOGY, 2009, 47 (02) :481-484
[10]   Preliminary observations on Mycobacterium spp. in dairy cattle in Ecuador [J].
Proano-Perez, Freddy ;
Rigouts, Leen ;
Brandt, Jef ;
Dorny, Pierre ;
Ron, Jorge ;
Chavez, Maria-Augusta ;
Rodriguez, Richar ;
Fissette, Krista ;
Van Aerde, Anita ;
Portaels, Francoise ;
Benitez-Ortiz, Washington .
AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2006, 75 (02) :318-323