Cutaneous Melanoma-A Review in Detection, Staging, and Management

被引:101
作者
Hartman, Rebecca I. [1 ,2 ]
Lin, Jennifer Y. [1 ,2 ]
机构
[1] Brigham & Womens Hosp, Dept Dermatol, 41 Ave Louis Pasteur,Room 319, Boston, MA 02115 USA
[2] Dana Farber Canc Inst, Melanoma Program, 450 Brookline Ave, Boston, MA 02115 USA
关键词
Melanoma; Malignant melanoma; Cutaneous melanoma; Immunotherapy; Targeted therapy; Sentinel lymph node biopsy; COMBINED NIVOLUMAB; LENTIGO MALIGNA; NODE BIOPSY; VITAMIN-D; CANCER; SURVIVAL; IPILIMUMAB; DERMOSCOPY; BRAF; DIAGNOSIS;
D O I
10.1016/j.hoc.2018.09.005
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Melanoma is an increasingly common cancer in the United States, although mortality has likely stabilized. Diagnosis relies on a skilled practitioner with the aid of dermoscopy and initial local surgical management is a mainstay of treatment. Recent changes in staging emphasize continued use of sentinel lymph node biopsy to aid in prognostication although routine complete lymph node dissection has fallen out of favor. Advances in systemic treatment options, including targeted and immunotherapy, have dramatically changed the treatment paradigm for advanced melanoma and improved outcome. Prevention via sun protection remains a critical tool in efforts to limit the burden of this disease.
引用
收藏
页码:25 / +
页数:15
相关论文
共 56 条
  • [1] Clinical whole-body skin examination reduces the incidence of thick melanomas
    Aitken, Joanne F.
    Elwood, Mark
    Baade, Peter D.
    Youl, Philippa
    English, Dallas
    [J]. INTERNATIONAL JOURNAL OF CANCER, 2010, 126 (02) : 450 - 458
  • [2] Genomic Classification of Cutaneous Melanoma
    Akbani, Rehan
    Akdemir, Kadir C.
    Aksoy, B. Arman
    Albert, Monique
    Ally, Adrian
    Amin, Samirkumar B.
    Arachchi, Harindra
    Arora, Arshi
    Auman, J. Todd
    Ayala, Brenda
    Baboud, Julien
    Balasundaram, Miruna
    Balu, Saianand
    Barnabas, Nandita
    Bartlett, John
    Bartlett, Pam
    Bastian, Boris C.
    Baylin, Stephen B.
    Behera, Madhusmita
    Belyaev, Dmitry
    Benz, Christopher
    Bernard, Brady
    Beroukhim, Rameen
    Bir, Natalie
    Black, Aaron D.
    Bodenheimer, Tom
    Boice, Lori
    Boland, Genevieve M.
    Bono, Riccardo
    Bootwalla, Moiz S.
    Bosenberg, Marcus
    Bowen, Jay
    Bowlby, Reanne
    Bristow, Christopher A.
    Brockway-Lunardi, Laura
    Brooks, Denise
    Brzezinski, Jakub
    Bshara, Wiam
    Buda, Elizabeth
    Burns, William R.
    Butterfield, Yaron S. N.
    Button, Michael
    Calderone, Tiffany
    Cappellini, Giancarlo Antonini
    Carter, Candace
    Carter, Scott L.
    Cherney, Lynn
    Cherniack, Andrew D.
    Chevalier, Aaron
    Chin, Lynda
    [J]. CELL, 2015, 161 (07) : 1681 - 1696
  • [3] Role of Sentinel Lymph Node Biopsy in Patients with Thin Melanoma
    Andtbacka, Robert H. I.
    Gershenwald, Jeffrey E.
    [J]. JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK, 2009, 7 (03): : 308 - 317
  • [4] [Anonymous], SEER Cancer Stat Facts: Ovarian Cancer
  • [5] [Anonymous], J AM ACAD DERMATOL
  • [6] [Anonymous], BMC CANC
  • [7] [Anonymous], 2012, BMJ BRIT MED J, DOI DOI 10.1136/BMJ.E4757
  • [8] [Anonymous], NCCN EVIDENCE BLOCKS
  • [9] KIT Gene Mutations and Copy Number in Melanoma Subtypes
    Beadling, Carol
    Jacobson-Dunlop, Erick
    Hodi, F. Stephen
    Le, Claudia
    Warrick, Andrea
    Patterson, Janice
    Town, Ajia
    Harlow, Amy
    Cruz, Frank, III
    Azar, Sharl
    Rubin, Brian P.
    Muller, Susan
    West, Rob
    Heinrich, Michael C.
    Corless, Christopher L.
    [J]. CLINICAL CANCER RESEARCH, 2008, 14 (21) : 6821 - 6828
  • [10] Screening for Skin Cancer US Preventive Services Task Force Recommendation Statement
    Bibbins-Domingo, Kirsten
    Grossman, David C.
    Curry, Susan J.
    Davidson, Karina W.
    Ebell, Mark
    Epling, John W., Jr.
    Garcia, Francisco A. R.
    Gillman, Matthew W.
    Kemper, Alex R.
    Krist, Alex H.
    Kurth, Ann E.
    Landefeld, C. Seth
    Mangione, Carol M.
    Phillips, William R.
    Phipps, Maureen G.
    Pignone, Michael P.
    Siu, Albert L.
    [J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2016, 316 (04): : 429 - 435