Case Report: Fatal Acute Liver Failure With Giant Cell Transformation in a Pediatric Patient Associated With MIS-C

被引：2

作者：

Bonilla Gonzalez, Carolina ^{[1
]}

Hincapie Echeverria, Marcela ^{[2
]}

Plazas Pachon, Rocio ^{[2
]}

Mora Umana, Paola ^{[2
]}

Diaz Gomez, Berlly Lucia ^{[3
]}

Gualdron Barreto, Nathalie ^{[1
]}

机构：

[1] Fdn Santafe Bogota, Dept Pediat, Pediat Intens Care Unit, Bogota, Colombia

[2] Pediat Residents Andes Univ, Fdn Santafe Bogota, Bogota, Colombia

[3] Fdn Santafe Bogota, Dept Pathol, Bogota, Colombia

来源：

FRONTIERS IN PEDIATRICS | 2022年 / 9卷

关键词：

liver failure; MIS-C; cytokine storm; SARS-CoV-2; case report;

D O I：

10.3389/fped.2021.780258

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Background: We describe the first pediatric case of a 10-month-old boy with MIS-C who developed fulminant acute liver failure with associated giant cell transformation and a fatal outcome, after ruling out other infectious, metabolic, genetic, and autoimmune causes of liver failure following the usual algorithms for approaching the etiology. Although the patient received the main treatment strategies for liver failure, he had a fatal outcome. A clinical autopsy was considered as part of the diagnostic approach, which showed evidence of giant cell transformation.

引用

页数：6

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