Trypanosoma cruzi I diversity: Towards the need of genetic subdivision?

被引：74

作者：

Guhl, Felipe ^{[1
]}

Ramirez, Juan David ^{[1
]}

机构：

[1] Univ Andes, CIMPAT, Bogota, Colombia

来源：

ACTA TROPICA | 2011年 / 119卷 / 01期

关键词：

Trypanosoma cruzi I; DTUs; Genetic variability; Mini-exon; Microsatellites; MINI-EXON GENE; CHAGAS-DISEASE; CYTOCHROME-B; PRIMER-PCR; LINEAGE-I; VARIABILITY; RANGELI; REGIONS; IDENTIFICATION; STOCKS;

D O I：

10.1016/j.actatropica.2011.04.002

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Trypanosoma cruzi the aethiological agent of Chagas disease, a complex zoonoses that affects the American continent is a genetically variable parasite subdivided into six Discrete Typing Units (DTUs). T. cruzi I is the most prevalent DTU affecting the northern countries of America with sporadical cases in the southern countries. T. cruzi I has shown great genetic diversity showing plausible subdivisions needed for this group. Recently. Tcl has gained novel importance because of the lately discovered relation with cardiomyopathy manifestations that raises the importance of establishing subdivisions within this DTU. (C) 2011 Elsevier BM. All rights reserved.

引用

页码：1 / 4

页数：4

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