Intracerebral hemorrhage in translational research

被引:9
作者
Zhang, Ruiyi [1 ,2 ]
Bai, Qian [1 ,2 ]
Liu, Yang [1 ,2 ]
Zhang, Yan [1 ,2 ]
Sheng, Zhaofu [1 ,2 ]
Xue, Mengzhou [1 ,2 ,5 ]
Yong, V. Wee [3 ,4 ,5 ]
机构
[1] Zhengzhou Univ, Affiliated Hosp 2, Dept Cerebrovasc Dis, Henan Joint Int Lab Intracerebral Hemorrhag Brain, Zhengzhou, Henan, Peoples R China
[2] Henan Med Key Lab Translat Cerebrovasc Dis, Zhengzhou, Henan, Peoples R China
[3] Univ Calgary, Hotchkiss Brain Inst, Calgary, AB, Canada
[4] Univ Calgary, Dept Clin Neurosci, Calgary, AB, Canada
[5] 2 Jingba Rd, Zhengzhou 450001, Henan, Peoples R China
来源
BRAIN HEMORRHAGES | 2020年 / 1卷 / 01期
基金
中国国家自然科学基金;
关键词
Intracerebral hemorrhage; Brain injury; Neuroinflammation; Neuroimmunology; Neuronal death; MATRIX METALLOPROTEINASES; MICROGLIA ACTIVATION; HEMATOMA RESOLUTION; CEREBRAL-HEMORRHAGE; CELL-CULTURE; SPOT SIGN; INJURY; BRAIN; BLOOD; THROMBIN;
D O I
10.1016/j.hest.2020.02.003
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Intracerebral hemorrhage (ICH) is a serious stroke subtype with high morbidity and mortality. The prog-nosis of ICH is poor. In recent years, there have been many studies on how to improve the prognosis of ICH. This article mainly summarizes the research progress of ICH in translational research, including its risk factors and pathogenesis, course of disease, primary and secondary ICH brain injury, its prevention and treatment strategies.(c) 2020 Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
引用
收藏
页码:13 / 18
页数:6
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