Next Stop for Fatty Acid Amide Hydrolase Inhibitors, the Clinic?

被引:1
作者
Piomelli, Daniele [1 ]
机构
[1] Univ Calif Irvine, Dept Anat & Neurobiol, 3101 Gillespie Neurosci Res Facil, Irvine, CA 92697 USA
关键词
ENDOCANNABINOID SYSTEM; NABILONE; EFFICACY;
D O I
10.1016/j.biopsych.2019.11.020
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
引用
收藏
页码:485 / 486
页数:2
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共 10 条
[1]   Cannabinoids for the treatment of mental disorders and symptoms of mental disorders: a systematic review and meta-analysis [J].
Black, Nicola ;
Stockings, Emily ;
Campbell, Gabrielle ;
Tran, Lucy T. ;
Zagic, Dino ;
Hall, Wayne D. ;
Farrell, Michael ;
Degenhardt, Louisa .
LANCET PSYCHIATRY, 2019, 6 (12) :995-1010
[2]   Reduced cellular expression and activity of the P129T mutant of human fatty acid amide hydrolase: evidence for a link between defects in the endocannabinoid system and problem drug use [J].
Chiang, KP ;
Gerber, AL ;
Sipe, JC ;
Cravatt, BF .
HUMAN MOLECULAR GENETICS, 2004, 13 (18) :2113-2119
[3]   THE EFFICACY AND SAFETY OF NABILONE (A SYNTHETIC CANNABINOID) IN THE TREATMENT OF ANXIETY [J].
FABRE, LF ;
MCLENDON, D .
JOURNAL OF CLINICAL PHARMACOLOGY, 1981, 21 (8-9) :S377-S382
[4]   The efficacy of nabilone, a synthetic cannabinoid, in the treatment of PTSD-associated nightmares: A preliminary randomized, double-blind, placebo-controlled cross-over design study [J].
Jetly, Rakesh ;
Heber, Alexandra ;
Fraser, George ;
Boisvert, Denis .
PSYCHONEUROENDOCRINOLOGY, 2015, 51 :585-588
[5]   Elevated Anandamide, Enhanced Recall of Fear Extinction, and Attenuated Stress Responses Following Inhibition of Fatty Acid Amide Hydrolase: A Randomized, Controlled Experimental Medicine Trial [J].
Mayo, Leah M. ;
Asratian, Anna ;
Linde, Johan ;
Morena, Maria ;
Haataja, Roosa ;
Hammar, Valter ;
Augier, Gaelle ;
Hill, Matthew N. ;
Heilig, Markus .
BIOLOGICAL PSYCHIATRY, 2020, 87 (06) :538-547
[6]   A Genetic Component to National Differences in Happiness [J].
Minkov, Michael ;
Bond, Michael Harris .
JOURNAL OF HAPPINESS STUDIES, 2017, 18 (02) :321-340
[7]   WHY DO ADOLESCENTS USE DRUGS - AGE, SEX, AND USER DIFFERENCES [J].
NOVACEK, J ;
RASKIN, R ;
HOGAN, R .
JOURNAL OF YOUTH AND ADOLESCENCE, 1991, 20 (05) :475-492
[8]   The endocannabinoid system as a target for novel anxiolytic drugs [J].
Patel, Sachin ;
Hill, Mathew N. ;
Cheer, Joseph F. ;
Wotjak, Carsten T. ;
Holmes, Andrew .
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS, 2017, 76 :56-66
[9]   Cannabinoid facilitation of fear extinction memory recall in humans [J].
Rabinak, Christine A. ;
Angstadt, Mike ;
Sripada, Chandra S. ;
Abelson, James L. ;
Liberzon, Israel ;
Milad, Mohammed R. ;
Phan, K. Luan .
NEUROPHARMACOLOGY, 2013, 64 :396-402
[10]   FAAH Gene Variation Moderates Stress Response and Symptom Severity in Patients with Posttraumatic Stress Disorder and Comorbid Alcohol Dependence [J].
Spagnolo, Primavera A. ;
Ramchandani, Vijay A. ;
Schwandt, Melanie L. ;
Kwako, Laura E. ;
George, David T. ;
Mayo, Leah M. ;
Hillard, Cecilia J. ;
Heilig, Markus .
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH, 2016, 40 (11) :2426-2434