What's new in neuromyelitis optica? A short review for the clinical neurologist

被引：26

作者：

Whittam, Daniel ^{[1
]}

Wilson, Martin ^{[1
]}

Hamid, Shahd ^{[1
]}

Keir, Geoff ^{[1
]}

Bhojak, Maneesh ^{[1
]}

Jacob, Anu ^{[1
]}

机构：

[1] Walton Ctr Neurol & Neurosurg NHS Trust, Lower Lane, Liverpool L9 7LJ, Merseyside, England

来源：

JOURNAL OF NEUROLOGY | 2017年 / 264卷 / 11期

关键词：

Optic neuritis; Myelitis; Aquaporin; Myelin oligodendrocyte glycoprotein; OLIGODENDROCYTE GLYCOPROTEIN ANTIBODIES; INTERLEUKIN-6 RECEPTOR BLOCKADE; STEM-CELL TRANSPLANTATION; SPECTRUM DISORDER; MULTIPLE-SCLEROSIS; DIAGNOSTIC-CRITERIA; COGNITIVE IMPAIRMENT; ASTROCYTIC DAMAGE; ACIDIC PROTEIN; ACUTE RELAPSES;

D O I：

10.1007/s00415-017-8445-8

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The evolution of neuromyelitis optica spectrum disorder (NMOSD) from a rare, incurable and misunderstood disease with almost universally poor outcomes to its present state in just over a decade is unprecedented in neurology and possibly in medicine. Our knowledge of NMOSD biology has led to the recognition of wider phenotypes, new disease mechanisms, and thus clinical trials of new and effective treatments. This article aims to update readers on the recent developments in NMOSD with particular emphasis on clinical advances, the 2015 diagnostic criteria, biomarkers, imaging, and therapeutic interventions.

引用

页码：2330 / 2344

页数：15

共 120 条

[1] Treatment of acute relapses in neuromyelitis optica: Steroids alone versus steroids plus plasma exchange [J].

Abboud, Hesham ;

Petrak, Alex ;

Mealy, Maureen ;

Sasidharan, Sarana ;

Siddique, Laila ;

Levy, Michael .

MULTIPLE SCLEROSIS JOURNAL, 2016, 22 (02) :185-192

[2] Protocol for a multicentre randomised controlled TRial of IntraVEnous immunoglobulin versus standard therapy the treatment of transverse myelitis in adults and children (STRIVE) [J].

Absoud, M. ;

Gadian, J. ;

Hellier, J. ;

Brex, P. A. ;

Ciccarelli, O. ;

Giovannoni, G. ;

Kelly, J. ;

McCrone, P. ;

Murphy, C. ;

Palace, J. ;

Pickles, A. ;

Pike, M. ;

Robertson, N. ;

Jacob, A. ;

Lim, M. .

BMJ OPEN, 2015, 5 (05)

[3] Rituximab in the treatment of Neuromyelitis optica: a multicentre Italian observational study [J].

Annovazzi, Pietro ;

Capobianco, M. ;

Moiola, L. ;

Patti, F. ;

Frau, J. ;

Uccelli, A. ;

Centonze, D. ;

Perini, P. ;

Tortorella, C. ;

Prosperini, L. ;

Lus, G. ;

Fuiani, A. ;

Falcini, M. ;

Martinelli, V. ;

Comi, G. ;

Ghezzi, A. .

JOURNAL OF NEUROLOGY, 2016, 263 (09) :1727-1735

[4] Intractable Vomiting as the Initial Presentation of Neuromyelitis Optica [J].

Apiwattanakul, Metha ;

Popescu, Bogdan F. ;

Matiello, Marcelo ;

Weinshenker, Brian G. ;

Lucchinetti, Claudia F. ;

Lennon, Vanda A. ;

McKeon, Andrew ;

Carpenter, Adam F. ;

Miller, Gary M. ;

Pittock, Sean J. .

ANNALS OF NEUROLOGY, 2010, 68 (05) :757-761

[5] Clinical improvement in a patient with neuromyelitis optica following therapy with the anti-IL-6 receptor monoclonal antibody tocilizumab [J].

Araki, Manabu ;

Aranami, Toshimasa ;

Matsuoka, Takako ;

Nakamura, Masakazu ;

Miyake, Sachiko ;

Yamamura, Takashi .

MODERN RHEUMATOLOGY, 2013, 23 (04) :827-831

[6] Efficacy of glatiramer acetate in neuromyelitis optica spectrum disorder: a multicenter retrospective study [J].

Ayzenberg, Ilya ;

Schoellhammer, Joanna ;

Hoepner, Robert ;

Hellwig, Kerstin ;

Ringelstein, Marius ;

Aktas, Orhan ;

Kuempfel, Tania ;

Krumbholz, Markus ;

Trebst, Corinna ;

Paul, Friedemann ;

Pache, Florence ;

Obermann, Mark ;

Zeltner, Lena ;

Schwab, Matthias ;

Berthele, Achim ;

Jarius, Sven ;

Kleiter, Ingo .

JOURNAL OF NEUROLOGY, 2016, 263 (03) :575-582

[7] Interleukin 6 Receptor Blockade in Patients With Neuromyelitis Optica Nonresponsive to Anti-CD20 Therapy [J].

Ayzenberg, Ilya ;

Kleiter, Ingo ;

Schroeder, Alexandra ;

Hellwig, Kerstin ;

Chan, Andrew ;

Yamamura, Takashi ;

Gold, Ralf .

JAMA NEUROLOGY, 2013, 70 (03) :394-397

[8] Alemtuzumab use in neuromyelitis optica spectrum disorders: a brief case series [J].

Azzopardi, Laura ;

Cox, Amanda L. ;

McCarthy, Claire L. ;

Jones, Joanne L. ;

Coles, Alasdair J. .

JOURNAL OF NEUROLOGY, 2016, 263 (01) :25-29

[9] Narcolepsy as an initial manifestation of neuromyelitis optica with antiaquaporin-4 antibody [J].

Baba, Toru ;

Nakashima, Ichiro ;

Kanbayashi, Takashi ;

Konno, Masatoshi ;

Takahashi, Toshiyuki ;

Fujihara, Kazuo ;

Misu, Tatsuro ;

Takeda, Atsushi ;

Shiga, Yusei ;

Ogawa, Hiromasa ;

Itoyama, Yasuto .

JOURNAL OF NEUROLOGY, 2009, 256 (02) :287-288

[10] Massive astrocyte destruction in neuromyelitis optica despite natalizumab therapy [J].

Barnett, M. H. ;

Prineas, J. W. ;

Buckland, M. E. ;

Parratt, J. D. E. ;

Pollard, J. D. .

MULTIPLE SCLEROSIS JOURNAL, 2012, 18 (01) :108-112

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