Efficient photoactivation of a Diels-Alderase ribozyme

被引：16

作者：

Nierth, Alexander ^{[1
]}

Singer, Marco ^{[1
]}

Jaeschke, Andres ^{[1
]}

机构：

[1] Univ Heidelberg, Inst Pharm & Mol Biotechnol, D-69120 Heidelberg, Germany

来源：

CHEMICAL COMMUNICATIONS | 2010年 / 46卷 / 42期

关键词：

LIGHT; RNA; ACTIVATION; NUCLEOBASES; EXPRESSION; MOLECULES;

D O I：

10.1039/c0cc03162c

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Here we report the first example of a photoactivatable ribozyme which catalyzes a bimolecular reaction of two small organic molecules with multiple turnover, under control of a photo-cleavable protecting group by exploiting the structural significance of a single hydrogen bond.

引用

页码：7975 / 7977

页数：3

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