Visualizing Nuclear RNA Editing

被引：0

作者：

Hochberg, Hodaya ^{[1
,2
]}

Shav-Tal, Yaron ^{[1
,2
]}

机构：

[1] Bar Ilan Univ, Mina & Everard Goodman Fac Life Sci, IL-5290002 Ramat Gan, Israel

[2] Bar Ilan Univ, Inst Nanotechnol, IL-5290002 Ramat Gan, Israel

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 2017年 / 42卷 / 11期

基金：

以色列科学基金会;

关键词：

NONCODING RNA; RETENTION; CELLS; DSRNA;

D O I：

10.1016/j.tibs.2017.09.004

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

RNA editing results in the site-specific conversion of adenosine to inosine in mRNAs. Genomics has revealed millions of editing sites in metazoans, but examining the spatial aspects of editing in cells has been challenging. A new method, inosineFISH (inoFISH), provides the ability to detect edited and unedited mRNAs within intact cells.

引用

收藏

页码：845 / 847

页数：3

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