Review of the flavonoids quercetin, hesperetin naringenin. Dietary sources, bioactivities, and epidemiology

被引:692
作者
Erlund, I [1 ]
机构
[1] Natl Publ Hlth Inst, Dept Hlth & Funct Capac, Biomarker Lab, SF-00300 Helsinki, Finland
关键词
flavonoids; quercetin; hesperetin; naringenin; bioavailability; metabolism; biomarker; epidemiology;
D O I
10.1016/j.nutres.2004.07.005
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
The bioactivities, dietary sources, bioavailability, metabolism, and epidemiology of 3 flavonoids, quercetin, hesperetin, and naringenin, are reviewed. The use of their plasma concentrations as biomarkers of dietary intake is also discussed. The compounds were chosen because of their significant dietary intakes and promising bioactivities, and in the case of quercetin, because epidemiological studies suggest protection against cardiovascular disease. (C) 2004 Elsevier Inc. All rights reserved.
引用
收藏
页码:851 / 874
页数:24
相关论文
共 172 条
[71]   CONTENT OF POTENTIALLY ANTICARCINOGENIC FLAVONOIDS OF 28 VEGETABLES AND 9 FRUITS COMMONLY CONSUMED IN THE NETHERLANDS [J].
HERTOG, MGL ;
HOLLMAN, PCH ;
KATAN, MB .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1992, 40 (12) :2379-2383
[72]   CONTENT OF POTENTIALLY ANTICARCINOGENIC FLAVONOIDS OF TEA INFUSIONS, WINES, AND FRUIT JUICES [J].
HERTOG, MGL ;
HOLLMAN, PCH ;
VANDEPUTTE, B .
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY, 1993, 41 (08) :1242-1246
[73]   Flavonol and flavone intake and the risk of cancer in male smokers (Finland) [J].
Tero Hirvonen ;
Jarmo Virtamo ;
Pasi Korhonen ;
Demetrius Albanes ;
Pirjo Pietinen .
Cancer Causes & Control, 2001, 12 (9) :797-802
[74]   Intake of flavonoids, carotenoids, vitamins C and E, and risk of stroke in male smokers [J].
Hirvonen, T ;
Virtamo, J ;
Korhonen, P ;
Albanes, D ;
Pietinen, P .
STROKE, 2000, 31 (10) :2301-2306
[75]   Intake of flavonols and flavones and risk of coronary heart disease in male smokers [J].
Hirvonen, T ;
Pietinen, P ;
Virtanen, M ;
Ovaskainen, ML ;
Häkkinen, S ;
Albanes, D ;
Virtamo, J .
EPIDEMIOLOGY, 2001, 12 (01) :62-67
[76]  
HIRVONEN T, 2001, THESIS NATL PUBLIC H
[77]   Relative bioavailability of the antioxidant flavonoid quercetin from various foods in man [J].
Hollman, PCH ;
vanTrijp, JMP ;
Buysman, MNCP ;
VanderGaag, MS ;
Mengelers, MJB ;
deVries, JHM ;
Katan, MB .
FEBS LETTERS, 1997, 418 (1-2) :152-156
[78]   ABSORPTION OF DIETARY QUERCETIN GLYCOSIDES AND QUERCETIN IN HEALTHY ILEOSTOMY VOLUNTEERS [J].
HOLLMAN, PCH ;
DEVRIES, JHM ;
VANLEEUWEN, SD ;
MENGELERS, MJB ;
KATAN, MB .
AMERICAN JOURNAL OF CLINICAL NUTRITION, 1995, 62 (06) :1276-1282
[79]   Absorption and disposition kinetics of the dietary antioxidant quercetin in man [J].
Hollman, PCH ;
vanderGaag, M ;
Mengelers, MJB ;
vanTrijp, JMP ;
deVries, JH ;
Katan, MB .
FREE RADICAL BIOLOGY AND MEDICINE, 1996, 21 (05) :703-707
[80]   The sugar moiety is a major determinant of the absorption of dietary flavonoid glycosides in man [J].
Hollman, PCH ;
Bijsman, MNCP ;
van Gameren, Y ;
Cnossen, EPJ ;
de Vries, JHM ;
Katan, MB .
FREE RADICAL RESEARCH, 1999, 31 (06) :569-573