Asymptomatic Canine Degenerative Valve Disease: Current and Future Therapies

被引：14

作者：

Gordon, Sonya G. ^{[1
]}

Saunders, Ashley B. ^{[1
]}

Wesselowski, Sonya R. ^{[1
]}

机构：

[1] Texas A&M Univ, Dept Small Anim Clin Sci, Coll Vet Med & Biomed Sci, Raymond Stotzer Pkwy, College Stn, TX 77843 USA

来源：

VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE | 2017年 / 47卷 / 05期

关键词：

Chronic; Mitral valve; Myxomatous; Preclinical; Stage B2; Treatment; CONGESTIVE-HEART-FAILURE; CHRONIC VALVULAR DISEASE; ANGIOTENSIN-ALDOSTERONE SYSTEM; KING CHARLES SPANIELS; PULMONARY-HYPERTENSION; MITRAL REGURGITATION; RISK-FACTORS; DOGS; REPAIR; ENALAPRIL;

D O I：

10.1016/j.cvsm.2017.04.003

中图分类号：

S85 [动物医学（兽医学）];

学科分类号：

0906 ;

摘要：

Degenerative valve disease (DVD) is the leading cause of heart disease and congestive heart failure (CHF) in the dog. The first published consensus statement provided guidelines for the diagnosis and treatment of DVD. Although treatment was not recommended in stage B1 DVD, consensus was not reached regarding evidence-based recommendations for treatment of stage B2 DVD. This article addresses the impact of new evidence on historical recommendations for stage B DVD and gives the reader a glimpse into possible future therapies. Management of common sequelae of DVD that can result in clinical signs that are not attributable to CHF is also discussed.

引用

页码：955 / +

页数：22

共 51 条

[1]

[Anonymous], EPIC TRIAL PIM PRECL

[2]

[Anonymous], INT CARD VET S DUBR

[3]

[Anonymous], INT CARD VET S OCT 2

[4]

[Anonymous], INT CARD VET S OCT 2

[5] Guidelines for the Diagnosis and Treatment of Canine Chronic Valvular Heart Disease [J].

Atkins, C. ;

Bonagura, J. ;

Ettinger, S. ;

Fox, P. ;

Gordon, S. ;

Haggstrom, J. ;

Hamlin, R. ;

Keene, B. ;

Luis-Fuentes, V. ;

Stepien, R. .

JOURNAL OF VETERINARY INTERNAL MEDICINE, 2009, 23 (06) :1142-1150

[6] Effects of long-term administration of enalapril on clinical indicators of renal function in dogs with compensated mitral regurgitation [J].

Atkins, CE ;

Brown, WA ;

Coats, JR ;

Crawford, MA ;

DeFrancesco, TC ;

Edwards, J ;

Fox, PR ;

Keene, BW ;

Lehmkuhl, L ;

Luethy, M ;

Meurs, K ;

Petrie, JP ;

Pipers, F ;

Rosenthal, S ;

Sidley, JA ;

Straus, J .

JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 2002, 221 (05) :654-658

[7] Results of the veterinary enalapril trial to prove reduction in onset of heart failure in dogs chronically treated with enalapril alone for compensated, naturally occurring mitral valve insufficiency [J].

Atkins, Clarke E. ;

Keene, Bruce W. ;

Brown, William A. ;

Coats, Julie R. ;

Crawford, Mary Ann ;

DeFrancesco, Teresa C. ;

Edwards, N. Joel ;

Fox, Phillip R. ;

Lehmkuhl, Linda B. ;

Luethy, Michael W. ;

Meurs, Kathryn M. ;

Petrie, Jean-Paul ;

Pipers, Frank S. ;

Rosenthal, Steven L. ;

Sidley, Jennifer A. ;

Straus, Justin H. .

JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION, 2007, 231 (07) :1061-1069

[8]

BEARDOW AW, 1993, J AM VET MED ASSOC, V203, P1023

[9] Efficacy of Spironolactone on Survival in Dogs with Naturally Occurring Mitral Regurgitation Caused by Myxomatous Mitral Valve Disease [J].

Bernay, F. ;

Bland, J. M. ;

Haggstrom, J. ;

Baduel, L. ;

Combes, B. ;

Lopez, A. ;

Kaltsatos, V. .

JOURNAL OF VETERINARY INTERNAL MEDICINE, 2010, 24 (02) :331-341

[10] Ultrastructural morphologic evaluation of the phenotype of valvular interstitial cells in dogs with myxomatous degeneration of the mitral valve [J].

Black, A ;

French, AT ;

Dukes-McEwan, J ;

Corcoran, BM .

AMERICAN JOURNAL OF VETERINARY RESEARCH, 2005, 66 (08) :1408-1414

← 1 2 3 4 5 6 →