Canine bronchomalacia: A clinicopathological study of 18 cases diagnosed by endoscopy

被引:27
作者
Adamama-Moraitou, Katerina K. [1 ]
Pardali, Dimitra [1 ]
Day, Michael J. [2 ]
Prassinos, Nikitas N. [3 ]
Kritsepi-Konstantinou, Maria [4 ]
Patsikas, Michail N. [5 ]
Rallis, Timoleon S. [1 ]
机构
[1] Aristotle Univ Thessaloniki, Fac Vet Med, Compan Anim Clin Med, Thessaloniki 54627, Greece
[2] Univ Bristol, Sch Vet Sci, Langford BS40 5DU, England
[3] Aristotle Univ Thessaloniki, Fac Vet Med, Compan Anim Clin Surg, Thessaloniki 54627, Greece
[4] Aristotle Univ Thessaloniki, Fac Vet Med, Diagnost Lab, Thessaloniki 54627, Greece
[5] Aristotle Univ Thessaloniki, Fac Vet Med, Compan Anim Clin Diagnost Imaging, Thessaloniki 54627, Greece
关键词
Bronchial collapse; Bronchoscopic features; Dogs; Histopathology; Microbial culture; BRONCHOALVEOLAR LAVAGE FLUID; TRACHEAL COLLAPSE; DOGS; SPECIMENS; DISEASE; COUGH;
D O I
10.1016/j.tvjl.2010.11.021
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
Canine bronchomalacia (BM) is characterized by weakness leading to collapse of the bronchial wall. A prospective study of 18 affected dogs (age range: 1-15 years) was undertaken to characterize the clinicopathological and histological features of BM. Poodles and Yorkshire terriers were commonly affected. Half of the dogs were overweight or obese. The clinical presentation was a mild, wheezing, chronic cough and pulmonary crackles were heard in 28% of the dogs. Compatible radiographic changes were present in 61% of the dogs. Using bronchoscopy, both lungs were affected in half of the animals, whereas in the others the disease appeared to affect predominantly the left lung. Analysis of bronchoalveolar lavage fluid and biopsies of bronchial mucosa revealed pure or mixed neutrophilic inflammation. Underlying infectious bronchitis was considered possible in 56% of the dogs. It was concluded that canine BM may present as an isolated clinical entity associated with infection and/or inflammation. (C) 2010 Elsevier Ltd. All rights reserved.
引用
收藏
页码:261 / 266
页数:6
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