Synthesis of biphenyl-based phosphines by Suzuki coupling

被引：36

作者：

Baillie, C ^{[1
]}

Chen, WP ^{[1
]}

Xiao, JL ^{[1
]}

机构：

[1] Univ Liverpool, Dept Chem, Laverhulme Ctr Innovat Catalysis, Liverpool L69 7ZD, Merseyside, England

来源：

TETRAHEDRON LETTERS | 2001年 / 42卷 / 51期

基金：

英国工程与自然科学研究理事会;

关键词：

phosphine ligands; biphenyl; Suzuki coupling; C-C coupling; palladium catalysts;

D O I：

10.1016/S0040-4039(01)01981-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A series of phosphine oxides has been synthesised by the palladium-catalysed Suzuki coupling of arylboronic acids with OPPh2(o-C6H4Br). Oil reduction with trichlorosilane. functionalised. biphenyl-based phosphine ligands were obtained in good yields. Our preliminary results indicate these ligands to be effective for palladium-catalysed C-C coupling reactions including the formation of their own oxides. (C) 2001 Elsevier Science Ltd. All rights reserved.

引用

页码：9085 / 9088

页数：4

共 18 条

[11] Palladium-catalyzed alpha-arylation of ketones
Palucki, M
Buchwald, SL
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (45) : 11108 - 11109
[12] An improved synthesis of functionalized biphenyl-based phosphine ligands
Tomori, H
Fox, JM
Buchwald, SL
[J]. JOURNAL OF ORGANIC CHEMISTRY, 2000, 65 (17) : 5334 - 5341
[13] Tsuruta H, 2001, SYNLETT, P999
[14] Highly active palladium catalysts for Suzuki coupling reactions
Wolfe, JP
Singer, RA
Yang, BH
Buchwald, SL
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1999, 121 (41) : 9550 - 9561
[15] Simple, efficient catalyst system for the palladium-catalyzed amination of aryl chlorides, bromides, and triflates
Wolfe, JP
Tomori, H
Sadighi, JP
Yin, JJ
Buchwald, SL
[J]. JOURNAL OF ORGANIC CHEMISTRY, 2000, 65 (04) : 1158 - 1174
[16] Wolfe JP, 1999, ANGEW CHEM INT EDIT, V38, P2413, DOI 10.1002/(SICI)1521-3773(19990816)38:16<2413::AID-ANIE2413>3.0.CO
[17] 2-H
[18] A catalytic asymmetric Suzuki coupling for the synthesis of axially chiral biaryl compounds
Yin, JJ
Buchwald, SL
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2000, 122 (48) : 12051 - 12052

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