Metal-free synthesis of 2-mercaptobenzothiazoles and 6-(4-substituted-1H-1,2,3-triazol-1-yl)-2-mercaptobenzothiazoles via microwave-assisted synthesis pathway

被引：2

作者：

Tung, Truong Thanh ^{[1
,2
]}

Huy, Luong Xuan ^{[1
,2
]}

机构：

[1] PHENIKAA Univ, Fac Pharm, Hanoi 12116, Vietnam

[2] PHENIKAA Univ, PHENIKAA Inst Adv Study PIAS, Hanoi, Vietnam

来源：

SYNTHETIC COMMUNICATIONS | 2020年 / 50卷 / 13期

关键词：

microwave-assisted synthesis; metal-free; 2-mercaptobenzothiazole; DERIVATIVES; BENZOTHIAZOLE; 2-MERCAPTO; DESIGN;

D O I：

10.1080/00397911.2020.1761984

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A simple, efficient, and metal-free methodology for the preparation of 2-mercaptobenzothiazole and derivatives in excellent yields via microwave-assisted pathway is reported. Our condition provides a convenient protocol for the synthesis of a diverse collection of 2-mercaptobenzothiazoles and 6-(4-substituted-1H-1,2,3-triazol-1-yl)-2-mercaptobenzothiazoles with a very simple purification process. This report provides an alternative protocol for fast access to the wide range of compounds for sequence synthesis and biological studies.

引用

页码：2007 / 2014

页数：8

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