Synthesizing a nanoparticle distribution in magnetic fluid hyperthermia

被引:7
作者
Di Barba, P. [1 ]
Dughiero, F. [2 ]
Sieni, E. [2 ]
机构
[1] Univ Pavia, Dept Elect Engn, I-27100 Pavia, Italy
[2] Univ Padua, Dept Elect Engn, Padua, Italy
关键词
Evolutionary computing; Magnetic nanoparticles; FE three-dimensional transient analysis; Nanotechnology; Magnetohydrodynamics; TISSUE; FIELD;
D O I
10.1108/03321641111152667
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
Purpose - The purpose of this paper is to present the synthesis of magnetic fluid characteristics, like diameter of nanoparficles (NPs) and their concentration, in order to obtain a prescribed temperature rate. An evolution strategy algorithm is used in the optimization procedure, while three-dimensional finite-element (FE) modelling is used for magnetic field and thermal field analysis in transient conditions. Design/methodology/approach - FE analysis has been used in order to compute the magnetic and thermal field in a suitable model of the tumor region. The power density due to NP has been accordingly derived. Findings - The NP distribution, giving a prescribed thermal response, is synthesized. Practical implications The proposed method can be used to design a therapeutic treatment based on magnetic fluid hyperthermia. Originality/value - The paper belongs to a streamline of innovative studies on computational hyperthermia.
引用
收藏
页码:1507 / 1516
页数:10
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