A COVID-19 epidemic model with latency period

被引:173
作者
Liu, Z. [1 ]
Magal, P. [2 ]
Seydi, O. [3 ]
Webb, G. [4 ]
机构
[1] Beijing Normal Univ, Sch Math Sci, Beijing 100875, Peoples R China
[2] Univ Bordeaux, France CNRS, IMB, UMR 5251, F-33400 Talence, France
[3] Ecole Polytech Thies, Dept Tronc Commun, Thies, Senegal
[4] Vanderbilt Univ, Math Dept, 221 Kirkland Hall, Nashville, TN 37235 USA
基金
中国国家自然科学基金;
关键词
Corona virus; Reported and unreported cases; Isolation; Quarantine; Public closings; Epidemic mathematical model;
D O I
10.1016/j.idm.2020.03.003
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
At the beginning of a COVID-19 infection, there is a period of time known as the exposed or latency period, before an infected person is capable of transmitting the infection to another person. We develop two differential equations models to account for this period. The first is a model that incorporates infected persons in the exposed class, before transmission is possible. The second is a model that incorporates a time delay in infected persons, before transmission is possible. We apply both models to the COVID-19 epidemic in China. We estimate the epidemiological parameters in the models, such as the transmission rate and the basic reproductive number, using data of reported cases. We thus evaluate the role of the exposed or latency period in the dynamics of a COVID-19 epidemic. (c) 2020 The Authors. Production and hosting by Elsevier B.V. on behalf of KeAi Communications Co., Ltd. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
引用
收藏
页码:323 / 337
页数:15
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