Colony-stimulating factor-1 exerts direct effects on the proliferation and invasiveness of endometrial epithelial cells

被引：15

作者：

Aligeti, Sabitha ^{[1
]}

Kirma, Nameer B. ^{[1
]}

Binkley, Peter A. ^{[1
]}

Schenken, Robert S. ^{[1
]}

Tekmal, Rajeshwar Rao ^{[1
]}

机构：

[1] Univ Texas Hlth Sci Ctr San Antonio, Dept Obstet & Gynecol, San Antonio, TX 78229 USA

来源：

FERTILITY AND STERILITY | 2011年 / 95卷 / 08期

关键词：

Colony-stimulating factor 1; c-fms; endometriosis; early lesion development; C-FMS; RETROGRADE MENSTRUATION; CONFIRMS ATTACHMENT; MESOTHELIAL CELLS; EXPRESSION; RECEPTOR; CULTURE; EXPLANTS; LESION; CSF-1;

D O I：

10.1016/j.fertnstert.2011.03.026

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Although macrophage colony-stimulating factor (CSF-1) has been suggested to play a role in maintaining the chronic inflammatory response in endometriosis, our data suggest that CSF-1 may also play a role in early endometriosis lesion formation. We have shown that CSF-1, in an autocrine fashion, has a direct effect on endometrial epithelial cell proliferation and attachment to peritoneal mesothelial cells, early steps in endometriosis lesion formation on the peritoneum. (Fertil Steril (R) 2011; 95: 2464-6. (C) 2011 by American Society for Reproductive Medicine.)

引用

页码：2464 / 2466

页数：3

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