Foodomics evaluation of bioactive compounds in foods

被引：56

作者：

Valdes, Alberto ^{[1
]}

Cifuentes, Alejandro ^{[1
]}

Leon, Carlos ^{[2
,3
,4
]}

机构：

[1] CSIC, CIAL, Food Lab, Madrid, Spain

[2] Univ Carlos III Madrid, Dept Bioengn, Madrid, Spain

[3] FJD, IIS, Med Regenerat & Bioingn Tisular, Madrid, Spain

[4] CIEMAT CIBERER U714, Epithelial Biomed Div, Madrid, Spain

来源：

TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2017年 / 96卷

关键词：

Foodomics; Food science; Bioactive compounds; Proteomics; Metabolomics; Transcriptomics; Cancer; Neurodegenerative disease; Health; Diet; CAPILLARY ELECTROMIGRATION METHODS; SHOTGUN PROTEOMIC ANALYSIS; MASS-SPECTROMETRY; GENE-EXPRESSION; CANCER-CELLS; QUANTITATIVE-ANALYSIS; ROSEMARY EXTRACT; FATTY-ACIDS; RED WINE; IDENTIFICATION;

D O I：

10.1016/j.trac.2017.06.004

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Foodomics involves the study of food and nutrition domains through the application and integration of advanced omics technologies, such as transcriptomics, proteomics and metabolomics. This integration, together with biostatistics, chemometrics and bioinformatics tools allows the evaluation of complex biological systems, like those involved in the underlying mechanisms of bioactive food compounds that help to interpret the association between dietary exposure and health. In this review, we present a critical discussion of the recent developments in Foodomics approaches (including metabolomics, proteomics and transcriptomics) to understand the bioactivity of food and food ingredients on health as well as for the discovery of novel biomarkers related to such activity. (C) 2017 Elsevier B.V. All rights reserved.

引用

页码：2 / 13

页数：12

共 122 条

[1] Recent advances in the application of capillary electromigration methods for food analysis and Foodomics [J].