Cataract surgery and the development or progression of age-related macular degeneration: A systematic review

被引:53
作者
Bockelbrink, Angelina [1 ]
Roll, Stephanie [1 ]
Ruether, Klaus [2 ]
Rasch, Andrej [3 ]
Greiner, Wolfgang [3 ]
Willich, Stefan N. [1 ]
机构
[1] Charite Univ Med Berlin, Med Ctr, Inst Social Med Epidemiol & Hlth Econ, D-10098 Berlin, Germany
[2] Univ Med Ctr, Charite Campus Virchow Clin, Dept Ophthalmol, Berlin, Germany
[3] Univ Bielefeld, Fac Publ Hlth, D-4800 Bielefeld, Germany
关键词
age-related macular degeneration; cataract surgery; systematic review;
D O I
10.1016/j.survophthal.2008.04.001
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Age-related macular degeneration and cataract are the most frequent eye disorders of elderly people worldwide. The aim of this systematic review was to evaluate the effect of cataract surgery on the development and progression of age-related macular degeneration. Data were collected by means of a systematic literature search in 28 databases and an additional update in Pubmed. Search results were evaluated using pre-defined inclusion and exclusion criteria. All relevant publications were rated in terms of scientific quality and analyzed regarding their results. The literature search generated a total of 2,827 hits. Seven publications on five observational studies and two non-randomized clinical trials were eligible for analysis. The observational studies provided some evidence for an increased incidence of late age-related macular degeneration, respectively, for a promoting influence of cataract surgery on the progression of early types of age-related macular degeneration. The clinical trials did yield inconsistent results. In conclusion, only a small number of published studies investigated the development or progression of age-related macular degeneration following cataract surgery. The scientific level of evidence of these articles was not high and results were inconsistent, nevertheless a promoting influence of cataract surgery on the progression of early age-related macular degeneration can be assumed.
引用
收藏
页码:359 / 367
页数:9
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