Synthesis and structure of 5,5-diethoxycarbonyl-l-pyrroline N-oxide (DECPO).: Application to superoxide radical trapping

被引：22

作者：

Karoui, H

Clément, JL

Rockenbauer, A

Siri, D

Tordo, P

机构：

[1] Univ Aix Marseille 1 & 3, CNRS, UMR 6517, Lab SREP,Ctr St Jerome, F-13397 Marseille, France

[2] Inst Chem, Chem Res Ctr, H-125 Budapest, Hungary

来源：

TETRAHEDRON LETTERS | 2004年 / 45卷 / 01期

基金：

匈牙利科学研究基金会;

关键词：

D O I：

10.1016/j.tetlet.2003.10.098

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

DECPO, a new analogue of EMPO was synthesized through a two-step synthetic pathway. Its structure and its application to trap superoxide were investigated. The ESR detection of the DECPO-OOH spin adduct is easy even at low concentration Of Superoxide. In comparison with DEPMPO, the trapping of superoxide with DECPO is faster and the detection of DECPO-OOH can be performed using a very low nitrone concentration (0.5 mM). (C) 2003 Elsevier Ltd. All rights reserved.

引用

页码：149 / 152

页数：4