Synthesis and structure of 5,5-diethoxycarbonyl-l-pyrroline N-oxide (DECPO).: Application to superoxide radical trapping

被引：22
作者：
Karoui, H
Clément, JL
Rockenbauer, A
Siri, D
Tordo, P
机构：
[1] Univ Aix Marseille 1 & 3, CNRS, UMR 6517, Lab SREP,Ctr St Jerome, F-13397 Marseille, France
[2] Inst Chem, Chem Res Ctr, H-125 Budapest, Hungary
来源：
TETRAHEDRON LETTERS | 2004年 / 45卷 / 01期
基金：
匈牙利科学研究基金会;
关键词：
D O I：
10.1016/j.tetlet.2003.10.098
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
DECPO, a new analogue of EMPO was synthesized through a two-step synthetic pathway. Its structure and its application to trap superoxide were investigated. The ESR detection of the DECPO-OOH spin adduct is easy even at low concentration Of Superoxide. In comparison with DEPMPO, the trapping of superoxide with DECPO is faster and the detection of DECPO-OOH can be performed using a very low nitrone concentration (0.5 mM). (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码：149 / 152
页数：4
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