Paraneoplastic Dermatoses: A Brief General Review and an Extensive Analysis of Paraneoplastic Pemphigus and Paraneoplastic Dermatomyositis

被引:39
作者
Didona, Dario [1 ]
Fania, Luca [2 ]
Didona, Biagio [3 ]
Eming, Ruediger [1 ]
Hertl, Michael [1 ]
Di Zenzo, Giovanni [4 ]
机构
[1] Philipps Univ, Dept Dermatol & Allergol, Marburg 35043, Germany
[2] IDI IRCCS, Div Dermatol 1, Rome 00167, Italy
[3] IDI IRCCS, Rare Dis Unit, Rome 00167, Italy
[4] IDI IRCCS, Mol & Cell Biol Lab, Rome 00167, Italy
关键词
diagnosis; neoplasia; paraneoplastic dermatomyositis; paraneoplastic dermatoses; paraneoplastic pemphigus; skin features; AUTOIMMUNE MULTIORGAN SYNDROME; PYODERMA-GANGRENOSUM; CUTANEOUS MANIFESTATIONS; SKIN-LESIONS; DESMOGLEIN; POLYMYOSITIS; DIAGNOSIS; DISEASE; AUTOANTIBODIES; RISK;
D O I
10.3390/ijms21062178
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Skin manifestations of systemic disease and malignancy are extremely polymorphous. Clinicians should be familiarized with paraneoplastic dermatoses in order to perform an early diagnosis of the underlying neoplasm. Lack of familiarity with cutaneous clues of internal malignancy may delay diagnosis and treatment of cancer. In this review, we described several paraneoplastic dermatoses and discussed extensively two paradigmatic ones, namely paraneoplastic pemphigus and paraneoplastic dermatomyositis.
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页数:15
相关论文
共 66 条
  • [1] Pyoderma gangrenosum: a review of pathogenesis and treatment
    Ahn, Christine
    Negus, Deborah
    Huang, William
    [J]. EXPERT REVIEW OF CLINICAL IMMUNOLOGY, 2018, 14 (03) : 225 - 233
  • [2] Pyoderma Gangrenosum: An Update on Pathophysiology, Diagnosis and Treatment
    Alavi, Afsaneh
    French, Lars E.
    Davis, Mark D.
    Brassard, Alain
    Kirsner, Robert S.
    [J]. AMERICAN JOURNAL OF CLINICAL DERMATOLOGY, 2017, 18 (03) : 355 - 372
  • [3] Antibodies against desmoglein 3 (Pemphigus vulgaris antigen) are present in sera from patients with paraneoplastic pemphigus and cause acantholysis in vivo in neonatal mice
    Amagai, M
    Nishikawa, T
    Nousari, HC
    Anhalt, GJ
    Hashimoto, T
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 1998, 102 (04) : 775 - 782
  • [4] PARANEOPLASTIC PEMPHIGUS - AN AUTOIMMUNE MUCOCUTANEOUS DISEASE ASSOCIATED WITH NEOPLASIA
    ANHALT, GJ
    KIM, S
    STANLEY, JR
    KORMAN, NJ
    JABS, DA
    KORY, M
    IZUMI, H
    RATRIE, H
    MUTASIM, D
    ARISSABDO, L
    LABIB, RS
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 1990, 323 (25) : 1729 - 1735
  • [5] T helper type 1-related molecules as well as interleukin-15 are hyperexpressed in the skin lesions of patients with pyoderma gangrenosum
    Antiga, E.
    Maglie, R.
    Volpi, W.
    Bianchi, B.
    Berti, E.
    Marzano, A. V.
    Caproni, M.
    [J]. CLINICAL AND EXPERIMENTAL IMMUNOLOGY, 2017, 189 (03) : 383 - 391
  • [6] Neutrophilic dermatoses Pyoderma gangrenosum and other bowel- and arthritis-associated neutrophilic dermatoses
    Ashchyan, Hovik J.
    Nelson, Caroline A.
    Stephen, Sasha
    James, William D.
    Micheletti, Robert G.
    Rosenbach, Misha
    [J]. JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY, 2018, 79 (06) : 1009 - 1024
  • [7] Auriemma M, 2014, GIORN ITAL DERMAT V, V149, P505
  • [8] Incidence and predictive factors for malignancies in 136 Japanese patients with dermatomyositis, polymyositis and clinically amyopathic dermatomyositis
    Azuma, Kohei
    Yamada, Hidehiro
    Ohkubo, Michiko
    Yamasaki, Yoshioki
    Yamasaki, Masaomi
    Mizushima, Machiko
    Ozaki, Shoichi
    [J]. MODERN RHEUMATOLOGY, 2011, 21 (02) : 178 - 183
  • [9] Calcinosis Cutis Occurring in Association With Autoimmune Connective Tissue Disease The Mayo Clinic Experience With 78 Patients, 1996-2009
    Balin, Samuel J.
    Wetter, David A.
    Andersen, Louise K.
    Davis, Mark D. P.
    [J]. ARCHIVES OF DERMATOLOGY, 2012, 148 (04) : 455 - 462
  • [10] Bendewald MJ, 2010, ARCH DERMATOL, V146, P26, DOI 10.1001/archdermatol.2009.328