Thrombosis in pediatric malignancy: a review and future perspectives with focus on management

被引:9
作者
Bordbar, Mohammadreza [1 ]
Karimi, Mehran [1 ]
Shakibazad, Nader [1 ]
机构
[1] Shiraz Univ Med Sci, Hematol Res Ctr, Shiraz, Iran
关键词
children; malignancy; venous thromboembolism; ACUTE LYMPHOBLASTIC-LEUKEMIA; VENOUS THROMBOEMBOLIC EVENTS; MOLECULAR-WEIGHT HEPARIN; TUMOR THROMBUS; ANTITHROMBOTIC THERAPY; ONCOLOGY PATIENTS; INCREASED RISK; L-ASPARAGINASE; WILMS-TUMOR; CHILDREN;
D O I
10.1097/MBC.0000000000000772
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Venous thromboembolism (VTE) result in significant morbidity and mortality in children with cancer. The cause of VTE in children with cancer is multifactorial and includes genetic predisposition (thrombophilia), disease-related factors, and treatment-related factors including use of central venous catheter (CVC), surgery, and chemotherapy. This review aims to examine current knowledge regarding the incidence, risk factors, clinical manifestation, evaluation, prevention, and management of thromboembolic events in children with cancer. Copyright (C) 2018 Wolters Kluwer Health, Inc. All rights reserved.
引用
收藏
页码:596 / 601
页数:6
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