Metal-Free Rapid Synthesis of 2-Aroylamino Naphtho[1,2-d]thiazoles

被引：1

作者：

Liu, Tianbao ^{[1
]}

Peng, Yanfen ^{[1
]}

Gui, Meifang ^{[1
]}

Zhang, Min ^{[1
]}

机构：

[1] Chizhou Univ, Anhui Higher Educ Inst, Key Lab Micronano Powder & Adv Energy Mat, Dept Chem & Mat Engn, Chizhou 247000, Anhui, Peoples R China

来源：

CHINESE JOURNAL OF ORGANIC CHEMISTRY | 2019年 / 39卷 / 11期

基金：

中国国家自然科学基金;

关键词：

naphtho[1,2-d]thiazole; thiourea; iodosobenzene diacetate; metal-free; CYANINE DYE; INTRAMOLECULAR CYCLIZATION; BOND FORMATION; FLUORESCENT; REACTIVITY; ENAMINONES; DNA;

D O I：

10.6023/cjoc201904029

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel and efficient approach has been developed to synthesize 2-aroylamino naphtho[1,2-d]thiazole compounds through the reaction between 3-[1-(4-substituted naphthyl)]-1-aroylthiourea and iodosobenzene diacetate (IBD) under ambient air. A library of naphtho[1,2-d]thiazole derivatives having a variety of substituents has been synthesized. A plausible reaction pathway has been predicted. This reaction offers a metal-free synthesis, broad substrate scope, easily accessible reactants, excellent regioselectivity, room temperature reaction conditions under ambient air. The reported method is the efficient approach for the synthesis of naphtho[1,2-d]thiazole derivatives.

引用

页码：3199 / 3206

页数：8

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